1,3-Dioxolane

CAS 646-06-0

U.S. production volumes are classified as confidential business information.

Molecular structure of 646-06-0
US productionCBI
Import value, 2024$3.5B
Top sourceIreland 57%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293299 · basket

EPA reports by year
2023
US production Confidential · Imports Confidential
2019
US production Confidential · Imports Confidential

These shares come from HS customs code 293299, which covers 229 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 57%IrelandNL 24%NetherlandsCH 8%SwitzerlandCN 5%ChinaIT 2%Italy
EPA-registered importers (4)
Cellmark Usa
Special Materials
Starchem Usa
Tilley Distribution

Why It Matters

Sectors
ConstructionPlastics & RubberPaints & CoatingsCore Chemicals
Downstream UsesNot recorded
FDA Shortage Status
No FDA shortage records

Industrial Uses

Used in 4 sectors as 2 functional roles.

  • •Solvent in Paint and Coating ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
  • •Solvent in Adhesive Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
  • •Intermediate in Plastics Material and Resin Manufacturing (100%)Processing as a reactant
  • •Solvent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
  • •Intermediate in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.04/gFluorochem UK
CountryUnited Kingdom
Pack$371.80 / 10 kg
Purity99.9%
Vendors8 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS646-06-0
PubChem CID12586
DTXSIDDTXSID4027284
FormulaC3H6O2
Mol. Weight74.08 g/mol
SMILESC1COCO1

Data Sources

Brief citations

1,3-Dioxolane (CAS 646-06-0) https://chemicalindependence.com/chemical/646-06-0/ EPA CompTox (DSSTox): DTXSID4027284. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID4027284 PubChem: 12586. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/12586 EPA Chemical Data Reporting: 646-06-0. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 646-06-0. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 293299 for CAS 646-06-0. Reporting year: 2024. https://usatrade.census.gov/