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Tizanidine hydrochloride

Drug ingredient

CAS 64461-82-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 64461-82-1
1 HCl
US productionNot reported
Import value, 2024$6.4B
Top sourceSingapore 36%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293499 · basket

These shares come from HS customs code 293499, which covers 575 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
SG 36%SingaporeIE 23%IrelandCN 11%ChinaCH 6%SwitzerlandIN 5%India
54 FDA-registered drug labelers
A-S Medication Solutions
Actavis Pharma, Inc.
Advagen Pharma Limited
Advanced Rx of Tennessee, LLC
Advanced Rx Pharmacy of Tennessee, LLC
Alembic Pharmaceuticals Inc.
Alembic Pharmaceuticals Limited
American Health Packaging
Aphena Pharma Solutions - Tennessee, LLC
Apotex Corp.
Ascend Laboratories, LLC
Asclemed USA, Inc.
Aurobindo Pharma Limited
AvKARE
AvPAK
Bryant Ranch Prepack
Cadila Pharmaceuticals Limited
Cardinal Health 107, LLC
Coupler LLC
Covis Pharma US, Inc
Direct_Rx
Dr. Reddy's Laboratories Limited
Farmak, a,s
Ingenus Pharmaceuticals, LLC
Legacy Pharma USA, Inc.
Major Pharmaceuticals
Medisca Inc.
Modavar Pharmaceuticals LLC
MYLAN LABORATORIES LIMITED
NCS HealthCare of KY, LLC dba Vangard Labs
Nivagen Pharmaceuticals, Inc.
NorthStar Rx LLC
Northwind Health Company, LLC
NuCare Pharmaceuticals, Inc.
PD-Rx Pharmaceuticals, Inc.
PHOENIX RX LLC
Preferred Pharmaceuticals Inc.
Professional Compounding Centers of America dba PCCA
Proficient Rx LP
Quality Care Products LLC
Redpharm Drug
REMEDYREPACK INC.
Rising Pharma Holdings, Inc.
Rosemont Pharmaceuticals, LLC
ST. MARY'S MEDICAL PARK PHARMACY
SUN PHARMACEUTICAL INDUSTRIES, INC.
Symed Labs Limited
TIZANIDINE HYDROCHLORIDE
Trifluent Pharma, LLC
Unichem Laboratories Limited, India
Unichem Pharmaceuticals (USA), Inc.
Viona Pharmaceuticals Inc
Zydus Lifesciences Limited
Zydus Pharmaceuticals (USA) Inc.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 7 drug and cosmetic product listings (FDA).

  • •tizanidine
  • •tizanidine hydrochloride
  • •Tizanidine HCL
  • •Tizanidne hydrochloride
  • •Ontralfy
  • •Zanaflex
  • •Tizandine
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$2.89/gAaron Chemicals LLC
CountryHong Kong
Pack$289.00 / 100 g
Purity98%
Vendors31 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

30 more vendors
VendorCountry$/gPackPurity
Angene ChemicalChina → Hong Kong$3.11100 g98%
A2B Chem LLCUnited States$3.4025 g98%
Combi-Blocks, Inc.United States$3.40100 g95%
BLD Pharmatech Ltd.China$3.76100 g98%
AA BLOCKSUnited States$3.8025 g98%
BLD Pharmatech Co., LimitedUnited States$4.14100 g98%
Ambeed, Inc.United States$4.14100 g98%
BLD Pharmatech GmbHGermany$5.205 g98%
AK Scientific SpecializedUnited States$12.001 g95%
AK Scientific, Inc.United States$16.001 g98%
InterbioscreenHong Kong$64.5010 g95%
TargetMol ChemicalsChina → United States$446.00500 mg99.96%
MolnovaChina$610.00200 mg99%
TargetMol Chemicals EUAustria$675.00200 mg99.96%
Apexbio Technology LLCUnited States$1106.00500 mg99.92%
Angene International LimitedUnited States$1400.00100 mg98%
Cayman EuropeEstonia$1506.54500 mg98%
MedChemExpress MCESweden$1645.60100 mg99.93%
AstaTech, IncUnited States$1710.00100 mg95%
MedKoo Biosciences, IncUnited States$2100.00500 mg98%
Axon MedchemNetherlands$2160.0050 mg100%
Princeton BioMolecular Research (SC)United States$2900.00100 mg90%
Vitas M Chemical LimitedHong Kong$3170.00100 mg90%
AngeneChina → Hong Kong$4266.6730 mg98%
Sigma-Aldrich (Rush Stock)Germany$4383.35200 mg—
Sigma-AldrichGermany$4383.35200 mg—
CliniSciences GmbHSwitzerland$5263.2025 mg99%
A2B Chem LLC (1 week)United States$6390.00100 mg98%
AA BLOCKS (1 week)United States$6750.00100 mg98%
Key Organics Ltd.United Kingdom$6900.0010 mg97%

Chemical Identity

CAS64461-82-1
PubChem CID114869
DTXSIDDTXSID9046990
FormulaC9H9Cl2N5S
Mol. Weight290.17 g/mol
SMILESC1CN=C(N1)NC2=C(C=CC3=NSN=C32)Cl.Cl

Data Sources

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Brief citations

Tizanidine hydrochloride (CAS 64461-82-1) https://chemicalindependence.com/chemical/64461-82-1/ PubChem: 114869. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/114869 FDA National Drug Code directory: CAS 64461-82-1. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293499 for CAS 64461-82-1. Reporting year: 2024. https://usatrade.census.gov/