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Cloxacillin sodium

Drug ingredient

CAS 642-78-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 642-78-4
1 Na⁺
US productionNot reported
Import value, 2024$78M
Top sourceItaly 33%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 294110 · basket

These shares come from HS customs code 294110, which covers 13 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IT 33%ItalyCN 31%ChinaBG 22%BulgariaES 8%SpainMX 3%Mexico
2 FDA-registered drug labelers
ACS Dobfar S.p.A
Fresenius Kabi iPSUM S.r.l.

Why It Matters

Sectors
Health
Downstream UsesNot recorded
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS642-78-4
PubChem CID23675320
DTXSIDDTXSID4045551
FormulaC19H17ClN3NaO5S
Mol. Weight457.9 g/mol
SMILESCC1=C(C(=NO1)C2=CC=CC=C2Cl)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)[O-].[Na+]

Data Sources

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Brief citations

Cloxacillin sodium (CAS 642-78-4) https://chemicalindependence.com/chemical/642-78-4/ PubChem: 23675320. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/23675320 FDA National Drug Code directory: CAS 642-78-4. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 294110 for CAS 642-78-4. Reporting year: 2024. https://usatrade.census.gov/