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Colchicine

Drug ingredient

CAS 64-86-8

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 64-86-8
US productionNot reported
Import value, 2024$171M
Top sourceSwitzerland 40%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293979 · basket

These shares come from HS customs code 293979, which covers 60 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CH 40%SwitzerlandCN 18%ChinaIT 14%ItalyDE 13%GermanyIN 10%India
43 FDA-registered drug labelers
A-S Medication Solutions
Actavis Pharma, Inc.
AGEPHA Pharma USA, LLC
Alchem International Private Ltd
Alkaloids Bioactives Private Limited
American Health Packaging
Amneal Pharmaceuticals LLC
Aphena Pharma Solutions - Tennessee, LLC
Ascend Laboratories, LLC
Aurobindo Pharma Limited
AvPAK
Bryant Ranch Prepack
Camber Pharmaceuticals, Inc.
Chartwell RX, LLC
Coupler LLC
Direct Rx
Dr.Reddys Laboratories, Inc.
Golden State Medical Supply, Inc.
Granules Pharmaceutical Inc.
Granules Pharmaceuticals Inc.
Harman Finochem Limited
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.
Hikma Pharmaceuticals USA Inc.
Hikma Specialty USA Inc.
Honour Lab Limited
Indena Spa
Ingenus Pharmaceuticals, LLC
Major Pharmaceuticals
Micro Labs Limited
Mylan Pharmaceuticals Inc.
NuCare Pharmaceuticals,Inc.
Par Active Technologies Private Limited
Par Health USA, LLC
Professional Compounding Centers of America
Proficient Rx LP
REMEDYREPACK INC.
Rising Pharma Holdings, Inc.
Scilex Pharmaceuticals Inc.
SOLARA ACTIVE PHARMA SCIENCES LIMITED
Strides Pharma Science Limited
Supriya Lifescience Limited
Takeda GmbH
Takeda Pharmaceuticals America, Inc.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 6 drug and cosmetic product listings (FDA).

  • •colchicine
  • •Probenecid and Colchicine
  • •Colcrys
  • •Mitigare
  • •Gloperba
  • •Lodoco
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$37.92/gAK Scientific Specialized
CountryUnited States
Pack$948.00 / 25 g
Purity95%
Vendors10 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

9 more vendors
VendorCountry$/gPackPurity
AK Scientific, Inc.United States$46.2025 g98%
TargetMol ChemicalsChina → United States$126.00500 mg99.96%
TargetMol Chemicals EUAustria$310.00100 mg99.96%
A2B Chem LLC (1 week)United States$392.00500 mg95%
Labotest KGGermany$453.001000 mg90%
Fulfilled by MolportLatvia$680.0050 mg99.96%
Otava, Ltd.Ukraine$4016.0025 mg95%
Vitas M Chemical LimitedHong Kong$9000.0010 mg90%
Princeton BioMolecular Research (SC)United States$10500.0010 mg90%

Chemical Identity

CAS64-86-8
PubChem CID6167
DTXSIDDTXSID5024845
FormulaC22H25NO6
Mol. Weight399.4 g/mol
SMILESCC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC

Data Sources

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Brief citations

Colchicine (CAS 64-86-8) https://chemicalindependence.com/chemical/64-86-8/ PubChem: 6167. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/6167 EPA TSCA Inventory: CAS 64-86-8. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293979 for CAS 64-86-8. Reporting year: 2024. https://usatrade.census.gov/