Tolbutamide

Drug ingredient

CAS 64-77-7

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 64-77-7
US productionNot reported
Import value, 2024$2.0B
Top sourceIreland 63%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293590 · basket

These shares come from HS customs code 293590, which covers 182 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 63%IrelandSG 14%SingaporeIN 7%IndiaCN 7%ChinaCH 2%Switzerland
2 FDA-registered drug labelers
Dipharma Francis Srl
Kothari Phytochemicals International

Why It Matters

Sectors
Health
Downstream UsesNot recorded
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$0.82/gAaron Chemicals LLC
CountryHong Kong
Pack$412.00 / 500 g
Purity98%
Vendors27 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS64-77-7
PubChem CID5505
DTXSIDDTXSID8021359
FormulaC12H18N2O3S
Mol. Weight270.35 g/mol
SMILESCCCCNC(=O)NS(=O)(=O)C1=CC=C(C=C1)C

Data Sources

Brief citations

Tolbutamide (CAS 64-77-7) https://chemicalindependence.com/chemical/64-77-7/ PubChem: 5505. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5505 EPA TSCA Inventory: CAS 64-77-7. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293590 for CAS 64-77-7. Reporting year: 2024. https://usatrade.census.gov/