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Tetracycline hydrochloride

Drug ingredient

CAS 64-75-5

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 64-75-5
1 HCl
US productionNot reported
Import value, 2024$62M
Top sourceChina 82%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 294130 · basket

These shares come from HS customs code 294130, which covers 10 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 82%ChinaCH 5%SwitzerlandBG 4%BulgariaTH 4%ThailandIT 2%Italy
21 FDA-registered drug labelers
Accuria, LLC
Actavis Pharma, Inc.
Amneal Pharmaceuticals NY LLC
AX Pharmaceutical Corp
Breckenridge Pharmaceutical, Inc.
Bryant Ranch Prepack
Chartwell RX, LLC.
CIPAN-Companhia Industrial Produtora de Antibiticos, S.A.
Endo USA, Inc.
Fagron Inc
FUJIAN FUKANG PHARMACEUTICAL CO., LTD.
H2-Pharma, LLC
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.
HONESTLY LLC
Ingenus Pharmaceuticals, LLC
LETCO MEDICAL, LLC
Medisca Inc.
Ningxia Qiyuan Pharmaceutical Co., Ltd.
Pharmaka Generics Inc.
Preferred Pharmaceuticals Inc.
VIADERMA DISTRIBUTION INC

Why It Matters

Sectors
Health
Downstream Uses

Appears in 13 drug and cosmetic product listings (FDA).

  • •Tetracycline Hydrochloride
  • •Pylera
  • •Viabecline
  • •Viaderma Vitastem First Aid Topical Antibiotic
  • •Honestly Battleborn First Aid for Real Man
  • •Bismuth Subcitrate Potassium, Metronidazole and Tetracycline Hydrochloride
  • •Tetracyte Topical Tetracycline Hydrochloride
  • •Vitastem First Aid Antibiotic
Show all 13
  • •ViaDerma Care Tetracycline HCl First Aid Antibiotic
  • •Vitastem
  • •Tetracyte First Aid and Antibiotic Topical
  • •Bismuth subcitrate potassium, Metronidazole, Tetracycline hydrochloride
  • •Vitastem-tetracycline hydrochloride
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$19.60/gApexbio Technology LLC
CountryUnited States
Pack$98.00 / 5 g
Purity98.48%
Vendors1 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS64-75-5
PubChem CID54704426
DTXSIDDTXSID6021321
FormulaC22H25ClN2O8
Mol. Weight480.9 g/mol
SMILESCC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.Cl

Data Sources

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Brief citations

Tetracycline hydrochloride (CAS 64-75-5) https://chemicalindependence.com/chemical/64-75-5/ PubChem: 54704426. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/54704426 EPA TSCA Inventory: CAS 64-75-5. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 294130 for CAS 64-75-5. Reporting year: 2024. https://usatrade.census.gov/