Formic acid
Drug ingredientCAS 64-18-6
This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.
US productionCBI
Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.
Import value, 2024$3M
Top sourceChina 38%
At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.
Why supply is unknownProduction is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023.
Where It Comes From
Customs basis: HS 291511 · exact
EPA reports by year
- 2023
- US production Confidential · Imports Confidential
- 2019
- US production Confidential · Imports Confidential
Source Countries
Country of origin for US imports, from Census customs data (2024).
CN 38%ChinaFI 21%FinlandES 16%SpainDE 13%GermanySE 10%Sweden
- Switzerland
- Israel
- Czech Republic
- India
EPA-registered manufacturers (6)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Basf Se · DE Germany
Basf
Hawkins
Hexion
Macdermid
Show all 6
Proviron
Domestic parents -- activity not disclosed (7)
EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.
Calfrac Well Services
Cellmark Basic Materials
Eastman Chemical
Emery Oleochemicals
Polyventive
Show all 7
Tannin
Transchem
EPA-registered importers (7)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Basf Se · DE Germany
Perstorp Ab · SE Sweden
Cascade Columbia
Chemical Distribution Network
Dow Chemical
Show all 7
Perstorp Polyols
Silver Fern Chemical
15 FDA-registered drug labelers
Apex Energetics Inc.
Be Well Medical dba Richard Clement Nutrition y Be Well Homeopathics
Bestmade Natural Products
Deseret Biologicals, Inc.
Dr. Donna Restivo DC
Energique, Inc.
Hahnemann Laboratories, INC.
King Bio Inc.
Marco Pharma International LLC.
Nestmann Pharma GmbH
PEKANA Naturheilmittel GmbH
Professional Complementary Health Formulas
RUBIMED AG
Supplement Clinic, LLC.
True Botanica, LLC
Why It Matters
Sectors
HealthAgricultureFoodEnergyElectronicsTransportationConstructionMetals & MiningPlastics & RubberTextilesConsumer ProductsPaper & PrintingCore Chemicals
Downstream Uses
Appears in 21 drug and cosmetic product listings (FDA).
- •Bestmade Natural Products BM203
- •Acidum Formicum
- •AI Miasm
- •Habifac
- •Homeoplex P
- •Formicum Acidum 6X
- •Geovita
- •REFL HS
Show all 21
- •C07 Strong Ligaments AND Joints
- •Arthritis Pain and Joint Relief
- •Allernest
- •S02 Aller-Total
- •Phase 6 Drops
- •Aspartame/MSG Detox
- •Gout Symptom Relief
- •Bolym-EX Drops
- •Selenium Combination 9245
- •Formiplus
- •D1 Organ Support
- •A05 Heavy Antitox
- •Detox I
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Industrial Uses
Used in 16 sectors as 16 functional roles.
- •Preservative in Agriculture, Forestry, Fishing and Hunting (50%)Processing as a reactant
- •pH regulating agent in All Other Chemical Product and Preparation Manufacturing (30%)Processing—incorporation into formulation, mixture, or reaction product
- •pH regulating agent in Paper Manufacturing (10%)Processing as a reactant
- •pH regulating agent in Textiles, apparel, and leather manufacturing (10%)Processing as a reactant
- •Preservative in Soap, Cleaning Compound, and Toilet Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Cleaning agent in Soap, Cleaning Compound, and Toilet Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Lubricating agent in All Other Basic Organic Chemical Manufacturing (100%)Processing as a reactant
- •Tanning agents not otherwise specified in Textiles, apparel, and leather manufacturing (100%)Processing—incorporation into article
- •Intermediate in All Other Basic Organic Chemical Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Plating agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Etching agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Chelating agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Corrosion inhibitor in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •pH regulating agent in Construction (40%)Processing—incorporation into formulation, mixture, or reaction product
- •Corrosion inhibitor in Oil and Gas Drilling, Extraction, and Support activitiesProcessing—incorporation into formulation, mixture, or reaction product
- •Monomers in Plastics Material and Resin Manufacturing (100%)Processing as a reactant
- •Intermediate in Plastics Material and Resin Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Processing aids, specific to petroleum production in Oil and Gas Drilling, Extraction, and Support activities (1%)Processing—incorporation into formulation, mixture, or reaction product
- •Soil amendments (fertilizers) in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (28%)Processing—incorporation into formulation, mixture, or reaction product
- •Binder in Plastics Material and Resin Manufacturing (72%)Processing—incorporation into formulation, mixture, or reaction product
- •pH regulating agent in Food, beverage, and tobacco product manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Solvent in All Other Basic Organic Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in Pharmaceutical and Medicine Manufacturing (15%)Processing—incorporation into formulation, mixture, or reaction product
- •Binder in Rubber Product Manufacturing (10%)Processing—incorporation into formulation, mixture, or reaction product
- •Chemical reaction regulator in Electrical Equipment, Appliance, and Component ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Chemical reaction regulator in Transportation Equipment Manufacturing (0%)Processing—incorporation into formulation, mixture, or reaction product
- •Cleaning agent in Fabricated Metal Product ManufacturingUse—non-incorporative activities
Vendor Pricing
$0.03/gA2B Chem LLC
CountryUnited States
Pack$15.00 / 500 g
Purity85%
Vendors8 available
Prices reflect listed pack sizes. Small research packs run far above bulk rates.
7 more vendors
| Vendor | Country Supplier country. Where available, shows shipping origin. When the supplier ships from a different country than where they are registered, both are shown. Most suppliers show registration country only. | $/g | Pack | Purity |
|---|---|---|---|---|
| AA BLOCKS | United States | $0.03 | 500 g | 85% |
| Sigma-Aldrich (Rush Stock) | Germany | $0.05 | 25 kg | 95% |
| Sigma-Aldrich | Germany | $0.05 | 25 kg | 95% |
| Fluorochem UK | United Kingdom | $0.09 | 1 kg | 99% |
| AK Scientific, Inc. | United States | $2.88 | 25 g | 99% |
| AstaTech, Inc | United States | $4.40 | 10 g | 95% |
| Labotest KG | Germany | $217.80 | 5000 mg | 90% |
Chemical Identity
CAS64-18-6
PubChem CID284
DTXSIDDTXSID2024115
FormulaCH2O2
Mol. Weight46.025 g/mol
SMILESC(=O)O
Data Sources
- EPA CompTox (DSSTox) · DTXSID2024115Retrieved 2026-04-06
- PubChem · compound 284Retrieved 2026-04-06
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- FDA National Drug Code directoryRetrieved 2026-04-07
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Formic acid (CAS 64-18-6) https://chemicalindependence.com/chemical/64-18-6/ EPA CompTox (DSSTox): DTXSID2024115. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID2024115 PubChem: 284. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/284 EPA Chemical Data Reporting: 64-18-6. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 64-18-6. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 291511 for CAS 64-18-6. Reporting year: 2024. https://usatrade.census.gov/