Manganese(II) acetate

Drug ingredient

CAS 638-38-0

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

Molecular structure of 638-38-0 — 1 Mn²⁺

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$64M

Top sourceNetherlands 37%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291529 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 291529, which covers 45 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

NL 37%NetherlandsCN 16%ChinaCA 15%CanadaIT 7%ItalyGB 5%United Kingdom

Finland
Belgium
Lithuania
Czech Republic
Switzerland
Spain
Turkey
Sweden
Singapore
Slovakia
Armenia

EPA-registered manufacturers (3)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Umicore Sv · BE Belgium

Shepherd Material Science

Umciore Usa

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Eastman Chemical

EPA-registered importers (2)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Umicore Sa · BE Belgium

Umicore Usa

Why It Matters

Sectors

HealthCore Chemicals

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Ferrodonna

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 3 sectors as 2 functional roles.

•Catalyst in Petrochemical Manufacturing (100%)Use—non-incorporative activities
•Catalyst in All Other Basic Organic Chemical ManufacturingProcessing as a reactant
•Intermediate in All Other Basic Inorganic Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product

Chemical Identity

CAS638-38-0

PubChem CID12525

DTXSIDDTXSID5027279

FormulaC4H6MnO4

Mol. Weight173.03 g/mol

SMILESCC(=O)[O-].CC(=O)[O-].[Mn+2]

Data Sources

EPA CompTox (DSSTox) · DTXSID5027279Retrieved 2026-04-06
PubChem · compound 12525Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Manganese(II) acetate (CAS 638-38-0) https://chemicalindependence.com/chemical/638-38-0/ EPA CompTox (DSSTox): DTXSID5027279. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID5027279 PubChem: 12525. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/12525 EPA Chemical Data Reporting: 638-38-0. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 638-38-0. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 291529 for CAS 638-38-0. Reporting year: 2024. https://usatrade.census.gov/