Phosphinic acid

CAS 6303-21-5

Companies reported imports and no US production of this chemical to EPA for 2023.

US productionZero

Import value, 2024$66M

Import volume234.1K lb

Import dependency100%

Top sourceChina 46%

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Phosphinic acid · US import value by year

2013: $54M · Peak 2022: $126M · 2024: $66M · 2025: $51M

Where It Comes From

Customs basis: HS 281119 · basket

EPA reports by year

2023: US production Zero · Imports 234.1K lb
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 281119, which covers 30 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 46%ChinaDE 17%GermanyMY 12%MalaysiaKR 5%South KoreaTW 5%Taiwan

Japan
Netherlands
Switzerland
Norway
Jordan
Italy
Czech Republic
United Kingdom

EPA-registered importers (2)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Special Materials

Wego Chemical Group

Why It Matters

Sectors

HealthCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 2 sectors as 2 functional roles.

•pH regulating agent in Pharmaceutical and Medicine Manufacturing (10%)Processing as a reactant
•Oxidizing agent in All Other Basic Inorganic Chemical Manufacturing (90%)Processing as a reactant

Chemical Identity

CAS6303-21-5

PubChem CID4124402

DTXSIDDTXSID90873902

FormulaH3O2P

Mol. Weight65.996 g/mol

SMILESO[PH2]=O

Data Sources

EPA CompTox (DSSTox) · DTXSID90873902Retrieved 2026-04-06
PubChem · compound 4124402Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Phosphinic acid (CAS 6303-21-5) https://chemicalindependence.com/chemical/6303-21-5/ EPA CompTox (DSSTox): DTXSID90873902. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID90873902 PubChem: 4124402. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/4124402 EPA Chemical Data Reporting: 6303-21-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 6303-21-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 281119 for CAS 6303-21-5. Reporting year: 2024. https://usatrade.census.gov/