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phenylalanine

Drug ingredient

CAS 63-91-2

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 63-91-2
US productionNot reported
Import value, 2024$503M
Top sourceChina 25%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292249 · basket

These shares come from HS customs code 292249, which covers 170 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 25%ChinaIN 17%IndiaSG 13%SingaporeIT 9%ItalyCH 7%Switzerland
18 FDA-registered drug labelers
Ajinomoto Co., Inc.
Ajinomoto Health & Nutrition North America Inc.
B. Braun Medical Inc.
Baxter Healthcare Company
Baxter Healthcare Corporation
BioActive Nutritional, Inc.
Deseret Biologicals, Inc.
Dr. Donna Restivo DC
Energique, Inc.
Fresenius Kabi USA, LLC
Guna spa
ICU Medical Inc.
InLight Creation, LLC.
KYOWA HAKKO BIO CO., LTD.
Nutritional Specialties, Inc.
Professional Complementary Health Formulas
Shanghai Ajinomoto Amino Acid Co., Ltd.
Shanghai Plumino Amino Acid Co., Ltd.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 25 drug and cosmetic product listings (FDA).

  • •Aminosyn-PF
  • •Plenamine
  • •D3 Organ Support
  • •Kabiven
  • •Clinimix
  • •Clinimix E
  • •Phenylalanine
  • •Phenylalanine Phenolic
Show all 25
  • •Clinisol
  • •ProSol
  • •TrophAmine
  • •Phenylalanine 1532
  • •Aminosyn II
  • •GUNA-Geriatrics
  • •GUNA-Matrix
  • •Detox III
  • •Osteobios
  • •Aspartame/MSG Detox
  • •Egg Allergen Mix
  • •Multi-Phenolic
  • •Travasol
  • •E.O.L.
  • •Perikabiven
  • •Metab
  • •Premasol - sulfite-free (Amino Acid)
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS63-91-2
PubChem CID6140
DTXSIDDTXSID4040763
FormulaC9H11NO2
Mol. Weight165.19 g/mol
SMILESC1=CC=C(C=C1)CC(C(=O)O)N

Data Sources

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Brief citations

phenylalanine (CAS 63-91-2) https://chemicalindependence.com/chemical/63-91-2/ PubChem: 6140. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/6140 EPA TSCA Inventory: CAS 63-91-2. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 292249 for CAS 63-91-2. Reporting year: 2024. https://usatrade.census.gov/