Riociguat

Drug ingredient

CAS 625115-55-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 625115-55-1
US productionNot reported
Import value, 2024$7.6B
Top sourceIreland 61%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293359 · basket

These shares come from HS customs code 293359, which covers 295 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 61%IrelandCH 30%SwitzerlandGB 2%United KingdomCN 2%ChinaIN 1%India
5 FDA-registered drug labelers
Alembic Pharmaceuticals Limited
Bayer AG
Bayer HealthCare Pharmaceuticals Inc.
MSN Life Sciences Private Limited
Patheon France S.A.S.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

  • •Adempas
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$48.00/gCombi-Blocks, Inc.
CountryUnited States
Pack$1200.00 / 25 g
Purity98%
Vendors22 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS625115-55-1
PubChem CID11304743
DTXSIDDTXSID50978109
FormulaC20H19FN8O2
Mol. Weight422.4 g/mol
SMILESCN(C1=C(N=C(N=C1N)C2=NN(C3=C2C=CC=N3)CC4=CC=CC=C4F)N)C(=O)OC

Data Sources

Brief citations

Riociguat (CAS 625115-55-1) https://chemicalindependence.com/chemical/625115-55-1/ PubChem: 11304743. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/11304743 FDA National Drug Code directory: CAS 625115-55-1. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293359 for CAS 625115-55-1. Reporting year: 2024. https://usatrade.census.gov/