Methoxyacetic acid

CAS 625-45-6

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$370M

Top sourceIndia 45%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291899 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 291899, which covers 139 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IN 45%IndiaCN 35%ChinaGB 7%United KingdomCO 3%ColombiaCH 3%Switzerland

Austria
Hungary
South Korea
Taiwan
Czech Republic
Mexico
Spain
Ukraine
Estonia
Australia
Israel
Singapore
Slovakia
Russia

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Pht International

EPA-registered importers (2)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Basf Se · DE Germany

Basf

Why It Matters

Sectors

Core Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Solvent in All Other Basic Organic Chemical ManufacturingProcessing as a reactant

Vendor Pricing

$0.03/gAaron Chemicals LLC

CountryHong Kong

Pack$17.00 / 500 g

Purity95%

Vendors23 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

22 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.04	1 kg	95%
A2B Chem LLC	United States	$0.10	500 g	95%
Chemscene	United States	$0.10	1 kg	—
AA BLOCKS	United States	$0.12	500 g	95%
Synthonix	United States	$0.16	500 g	95%
AK Scientific Specialized	United States	$0.20	500 g	98%
ALFA AESAR	Germany	$0.24	1 kg	97%
Combi-Blocks, Inc.	United States	$0.25	1 kg	98%
AK Scientific, Inc.	United States	$0.27	500 g	99%
AstaTech, Inc	United States	$0.34	250 g	98%
Ambeed, Inc.	United States	$0.38	100 g	98%
Sigma-Aldrich (Rush Stock)	Germany	$0.54	250 g	98%
Sigma-Aldrich	Germany	$0.54	250 g	98%
MedChemExpress MCE	Sweden	$0.75	100 g	99.97%
Angene International Limited	United States	$3.28	25 g	99%
Interbioscreen	Hong Kong	$24.00	10 g	95%
Labotest KG	Germany	$453.00	1000 mg	90%
Otava, Ltd.	Ukraine	$2280.00	50 mg	95%
Otava, Ltd. (2 weeks)	Ukraine	$2724.00	50 mg	95%
Angene	China → Hong Kong	$4266.67	30 mg	98%
Asinex	Netherlands	$8651.50	100 mg	90%
TimTec, LLC (back-ordered)	United States	$32000.00	15 mg	94%

Chemical Identity

CAS625-45-6

PubChem CID12251

DTXSIDDTXSID1031591

FormulaC3H6O3

Mol. Weight90.08 g/mol

SMILESCOCC(=O)O

Data Sources

EPA CompTox (DSSTox) · DTXSID1031591Retrieved 2026-04-06
PubChem · compound 12251Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Methoxyacetic acid (CAS 625-45-6) https://chemicalindependence.com/chemical/625-45-6/ EPA CompTox (DSSTox): DTXSID1031591. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID1031591 PubChem: 12251. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/12251 EPA Chemical Data Reporting: 625-45-6. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 625-45-6. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 291899 for CAS 625-45-6. Reporting year: 2024. https://usatrade.census.gov/