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Dimethyl fumarate

Drug ingredient

CAS 624-49-7

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 624-49-7
US productionNot reported
Import value, 2024$139M
Top sourceChina 67%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291719 · basket

These shares come from HS customs code 291719, which covers 176 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 67%ChinaCA 13%CanadaAT 4%AustriaIN 4%IndiaJP 4%Japan
39 FDA-registered drug labelers
A-S Medication Solutions
Accord Healthcare Inc.
Amneal Pharmaceuticals NY LLC
Amoli Organics (A Division of Umedica Laboratories Pvt.Ltd.)
Arevipharma GmbH
Ascend Laboratories, LLC
Aurobindo Pharma Limited
Biogen Inc.
Camber Pharmaceuticals, Inc.
Cipla USA Inc.
CivicaScript LLC
DOTTIKON EXCLUSIVE SYNTHESIS AG
Dr. Reddy's Laboratories Inc.
Dr.Reddy's Laboratories Limited
Glenmark Pharmaceuticals Inc., USA
Golden State Medical Supply, Inc.
Granules India Ltd
HONOUR LAB LIMITED
Janssen Cilag SpA
Laboratorium Ofichem B.V.
Macleods Pharmaceuticals Limited
MSN LABORATORIES PRIVATE LIMITED
MSN Organics Private Limited
MYLAN LABORATORIES LIMITED
NURAY CHEMICALS PRIVATE LIMITED
Optimus Drugs Private Limited
Quallent Pharmaceuticals Health LLC
SHILPA PHARMA LIFESCIENCES LIMITED
Sigma-Aldrich Production GmbH
Sionc Pharmaceutical Private Limited
SOLA Pharmaceuticals, LLC
Solco Healthcare US, LLC
SUN PHARMACEUTICAL INDUSTRIES, INC.
Upsher-Smith Laboratories, LLC
Veranova, L.P.
Viyash Life Sciences Private Limited
Zhejiang Huahai Pharmaceutical Co., Ltd.
Zydus Lifesciences Limited
Zydus Pharmaceuticals USA Inc.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

  • •Dimethyl Fumarate
  • •Tecfidera
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$10.40/gApexbio Technology LLC
CountryUnited States
Pack$52.00 / 5 g
Purity99.53%
Vendors1 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS624-49-7
PubChem CID637568
DTXSIDDTXSID4060787
FormulaC6H8O4
Mol. Weight144.12 g/mol
SMILESCOC(=O)C=CC(=O)OC

Data Sources

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Brief citations

Dimethyl fumarate (CAS 624-49-7) https://chemicalindependence.com/chemical/624-49-7/ PubChem: 637568. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/637568 EPA TSCA Inventory: CAS 624-49-7. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 291719 for CAS 624-49-7. Reporting year: 2024. https://usatrade.census.gov/