Methyl butyrate

CAS 623-42-7

EPA’s 2023 records show zero U.S. production of this chemical.

US productionZero

Import value, 2024$63M

Import volumeCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Top sourceChina 22%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291560 · basket

EPA reports by year

2023: US production Zero · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 291560, which covers 183 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 22%ChinaDE 19%GermanySE 14%SwedenJP 13%JapanIN 9%India

Ireland
South Korea
United Arab Emirates
Russia
Ukraine
Israel
Brazil
Canada

EPA-registered importers (2)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Pht International

Why It Matters

Sectors

Core Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Intermediate in All Other Basic Organic Chemical Manufacturing (100%)Processing as a reactant

Vendor Pricing

$0.03/gSigma-Aldrich (Rush Stock)

CountryGermany

Pack$589.85 / 20 kg

Purity98%

Vendors6 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

5 more vendors

Vendor	Country	$/g	Pack	Purity
Sigma-Aldrich	Germany	$0.03	20 kg	98%
A2B Chem LLC	United States	$0.40	100 g	95%
Combi-Blocks, Inc.	United States	$0.40	100 g	95%
AA BLOCKS	United States	$0.52	100 g	95%
Labotest KG	Germany	$217.80	5000 mg	90%

Chemical Identity

CAS623-42-7

PubChem CID12180

DTXSIDDTXSID5047083

FormulaC5H10O2

Mol. Weight102.13 g/mol

SMILESCCCC(=O)OC

Data Sources

EPA CompTox (DSSTox) · DTXSID5047083Retrieved 2026-04-06
PubChem · compound 12180Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Methyl butyrate (CAS 623-42-7) https://chemicalindependence.com/chemical/623-42-7/ EPA CompTox (DSSTox): DTXSID5047083. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID5047083 PubChem: 12180. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/12180 EPA Chemical Data Reporting: 623-42-7. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 623-42-7. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 291560 for CAS 623-42-7. Reporting year: 2024. https://usatrade.census.gov/