Tradipitant

Drug ingredient

CAS 622370-35-8

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$1.3B

Top sourceChina 32%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293339 · basket

These shares come from HS customs code 293339, which covers 397 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 32%ChinaIN 15%IndiaDE 10%GermanyBE 9%BelgiumCH 8%Switzerland

Taiwan
Ukraine
Sweden
Argentina
Canada
Finland
Malta
Israel
Netherlands
Denmark
United Arab Emirates
Mexico
Brunei
Slovakia
Australia
South Africa
Poland
Latvia
Lithuania
Estonia
Slovenia
Czech Republic
Croatia
Hong Kong

1 FDA-registered drug labeler

Vanda Pharmaceuticals Inc.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Nereus

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$2240.00/gCombi-Blocks (back-ordered)

CountryUnited States

Pack$560.00 / 250 mg

Purity95%

Vendors13 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

12 more vendors

Vendor	Country	$/g	Pack	Purity
Aaron Chemicals LLC	Hong Kong	$2720.00	100 mg	97%
Angene Chemical	China → Hong Kong	$2750.00	100 mg	97%
A2B Chem LLC	United States	$3050.00	100 mg	98%
AstaTech, Inc	United States	$3820.00	100 mg	95%
AA BLOCKS	United States	$3980.00	100 mg	98%
BLD Pharmatech Ltd.	China	$4300.00	50 mg	99%
MedKoo Biosciences, Inc	United States	$4650.00	1 g	98%
Molnova	China	$6620.00	100 mg	99%
TargetMol Chemicals	China → United States	$7360.00	100 mg	99.98%
Angene International Limited	United States	$7740.00	50 mg	95%
MedChemExpress MCE	Sweden	$12124.20	100 mg	99.95%
Cayman Europe	Estonia	$27703.20	25 mg	98%

Chemical Identity

CAS622370-35-8

PubChem CID9916461

DTXSIDDTXSID801045805

FormulaC28H16ClF6N5O

Mol. Weight587.9 g/mol

SMILESC1=CC=C(C(=C1)C(=O)C2=C(N=CC=C2)C3=C(N(N=N3)CC4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F)C5=CC=NC=C5)Cl

Data Sources

PubChem · compound 9916461Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Tradipitant (CAS 622370-35-8) https://chemicalindependence.com/chemical/622370-35-8/ PubChem: 9916461. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/9916461 FDA National Drug Code directory: CAS 622370-35-8. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293339 for CAS 622370-35-8. Reporting year: 2024. https://usatrade.census.gov/