Acetamide, N-(3-aminophenyl)-, hydrochloride (1:1)

CAS 621-35-2

EPA’s 2023 records show zero U.S. production of this chemical.

US productionZero

Import value, 2024$872M

Import volumeCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Top sourceSwitzerland 44%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292429 · basket

EPA reports by year

2023: US production Zero · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 292429, which covers 203 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CH 44%SwitzerlandCN 19%ChinaIN 12%IndiaJP 9%JapanIE 6%Ireland

Taiwan
United Kingdom
El Salvador
Colombia
Ukraine
Brazil
Guatemala
Belgium
Netherlands
Turkey
Sweden
Greece
Canada
Israel
New Zealand
Latvia
Lithuania
Finland
Slovakia
Australia
Hong Kong
Czech Republic
Armenia
Poland

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Archroma U.S

Why It Matters

Sectors

Textiles

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Intermediate in Synthetic Dye and Pigment Manufacturing (100%)Processing as a reactant

Vendor Pricing

$0.24/gAaron Chemicals LLC

CountryHong Kong

Pack$122.00 / 500 g

Purity95%

Vendors13 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

12 more vendors

Vendor	Country	$/g	Pack	Purity
BLD Pharmatech Co., Limited	United States	$0.25	500 g	95%
BLD Pharmatech Ltd.	China	$0.25	500 g	95%
Ambeed, Inc.	United States	$0.25	500 g	95%
A2B Chem LLC	United States	$0.27	100 g	95%
Angene Chemical	China → Hong Kong	$0.28	500 g	95%
AA BLOCKS	United States	$0.30	100 g	95%
Combi-Blocks, Inc.	United States	$0.30	500 g	95%
BLD Pharmatech GmbH	Germany	$0.48	25 g	95%
AstaTech (2 weeks)	United States	$0.57	500 g	95%
AK Scientific, Inc.	United States	$0.67	100 g	98%
Angene International Limited	United States	$1.39	100 g	98%
Angene	China → Hong Kong	$4266.67	30 mg	95%

Chemical Identity

CAS621-35-2

PubChem CID458805

DTXSIDDTXSID90883506

FormulaC8H11ClN2O

Mol. Weight186.64 g/mol

SMILESCC(=O)NC1=CC=CC(=C1)N.Cl

Data Sources

EPA CompTox (DSSTox) · DTXSID90883506Retrieved 2026-04-06
PubChem · compound 458805Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2019 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Acetamide, N-(3-aminophenyl)-, hydrochloride (1:1) (CAS 621-35-2) https://chemicalindependence.com/chemical/621-35-2/ EPA CompTox (DSSTox): DTXSID90883506. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID90883506 PubChem: 458805. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/458805 EPA Chemical Data Reporting: 621-35-2. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 621-35-2. Reporting year: 2019. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292429 for CAS 621-35-2. Reporting year: 2024. https://usatrade.census.gov/