Methacholine chloride

Drug ingredient

CAS 62-51-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$108M

Top sourceChina 14%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292390 · basket

These shares come from HS customs code 292390, which covers 130 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 14%ChinaGB 13%United KingdomDE 11%GermanyIN 10%IndiaTW 10%Taiwan

Israel
Indonesia
Sweden
Turkey
United Arab Emirates
Malaysia
Singapore
Lithuania
Brazil
Hong Kong
Australia
Belgium
Ukraine

3 FDA-registered drug labelers

Flamma S.p.A.

Flamma USA LLC

Methapharm Inc.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Provocholine

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$1.36/gAA BLOCKS

CountryUnited States

Pack$681.00 / 500 g

Purity98%

Vendors19 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

18 more vendors

Vendor	Country	$/g	Pack	Purity
A2B Chem LLC	United States	$3.44	100 g	—
Aaron Chemicals LLC	Hong Kong	$3.67	100 g	98%
Angene Chemical	China → Hong Kong	$3.70	100 g	98%
AK Scientific, Inc.	United States	$4.72	25 g	98%
AstaTech, Inc	United States	$4.80	25 g	98%
Combi-Blocks, Inc.	United States	$4.80	25 g	95%
Cayman Europe	Estonia	$6.85	25 g	95%
Fluorochem UK	United Kingdom	$6.86	5 g	98%
Sigma-Aldrich (Rush Stock)	Germany	$7.57	100 g	98%
Sigma-Aldrich	Germany	$7.57	100 g	98%
Angene International Limited	United States	$8.68	25 g	98%
MedKoo Biosciences, Inc	United States	$9.50	100 g	98%
TargetMol Chemicals	China → United States	$198.00	1 g	99.74%
Molnova	China	$390.00	200 mg	99%
Apexbio Technology LLC	United States	$450.00	200 mg	98%
Labotest KG	Germany	$453.00	1000 mg	90%
MedChemExpress MCE	Sweden	$895.40	100 mg	98%
Angene	China → Hong Kong	$4266.67	30 mg	98%

Chemical Identity

CAS62-51-1

PubChem CID6114

DTXSIDDTXSID7023271

FormulaC8H18ClNO2

Mol. Weight195.69 g/mol

SMILESCC(C[N+](C)(C)C)OC(=O)C.[Cl-]

Data Sources

PubChem · compound 6114Retrieved 2026-04-07
EPA TSCA InventoryRetrieved 2026-04-24
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Methacholine chloride (CAS 62-51-1) https://chemicalindependence.com/chemical/62-51-1/ PubChem: 6114. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/6114 EPA TSCA Inventory: CAS 62-51-1. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 292390 for CAS 62-51-1. Reporting year: 2024. https://usatrade.census.gov/