Calcium disodium ethylenediaminetetraacetate

Drug ingredient

CAS 62-33-9

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

Molecular structure of 62-33-9 — 2 Na⁺ · 1 Ca²⁺

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$503M

Top sourceChina 25%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292249 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 292249, which covers 170 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 25%ChinaIN 17%IndiaSG 13%SingaporeIT 9%ItalyCH 7%Switzerland

Argentina
Poland
Portugal
Lithuania
Ukraine
Finland
Spain
Egypt
Sweden
Austria
Israel
Latvia
Belgium
Ireland
Mexico
Australia
Peru
Czech Republic
Colombia
Hong Kong

EPA-registered manufacturers (4)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Conklin

Hawkins

Hydrite Chemical

The Andersons

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Icl Specialty Products North America

EPA-registered importers (4)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Basf Se · DE Germany

Basf

Nedam

Valagro/Syngenta Biologicals

Why It Matters

Sectors

HealthAgricultureConsumer Products

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Edetate Calcium Disodium

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 4 sectors as 3 functional roles.

•Chelating agent in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (100%)Processing—repackaging
•Soil amendments (fertilizers) in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Soil amendments (fertilizers) in Wholesale and Retail Trade (100%)Processing—incorporation into formulation, mixture, or reaction product
•CBI in CBICBI
•Soil amendments (fertilizers) in Agriculture, Forestry, Fishing and Hunting (100%)Processing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.04/gAaron Chemicals LLC

CountryHong Kong

Pack$10.00 / 250 g

Purity98%

Vendors17 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

16 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.05	250 g	98%
BLD Pharmatech Ltd.	China	$0.05	1 kg	98%
Ambeed, Inc.	United States	$0.05	1 kg	98%
BLD Pharmatech Co., Limited	United States	$0.06	500 g	98%
BLD Pharmatech GmbH	Germany	$0.06	500 g	98%
A2B Chem LLC	United States	$0.07	100 g	98%
AA BLOCKS	United States	$0.09	100 g	98%
Apollo Scientific UK	United Kingdom	$0.10	25 kg	98%
Angene International Limited	United States	$0.28	500 g	98%
Combi-Blocks, Inc.	United States	$0.30	500 g	97%
AK Scientific Specialized	United States	$0.59	100 g	95%
AK Scientific, Inc.	United States	$0.84	100 g	98%
AstaTech (2 weeks)	United States	$3.68	25 g	95%
TargetMol Chemicals	China → United States	$29.00	1 g	99.51%
Molnova	China	$922.00	500 mg	99%
Angene	China → Hong Kong	$4266.67	30 mg	98%

Chemical Identity

CAS62-33-9

PubChem CID6093170

DTXSIDDTXSID2036409

FormulaC10H12CaN2Na2O8

Mol. Weight374.27 g/mol

SMILESC(CN(CC(=O)[O-])CC(=O)[O-])N(CC(=O)[O-])CC(=O)[O-].[Na+].[Na+].[Ca+2]

Data Sources

EPA CompTox (DSSTox) · DTXSID2036409Retrieved 2026-04-06
PubChem · compound 6093170Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Calcium disodium ethylenediaminetetraacetate (CAS 62-33-9) https://chemicalindependence.com/chemical/62-33-9/ EPA CompTox (DSSTox): DTXSID2036409. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID2036409 PubChem: 6093170. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/6093170 EPA Chemical Data Reporting: 62-33-9. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 62-33-9. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292249 for CAS 62-33-9. Reporting year: 2024. https://usatrade.census.gov/