Dihydroergotamine mesylate

Drug ingredient

CAS 6190-39-2

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$6M

Top sourceCzech Republic 36%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293969 · basket

These shares come from HS customs code 293969, which covers 7 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CZ 36%Czech RepublicJP 30%JapanIT 17%ItalyCN 15%ChinaCA 1%Canada

Switzerland
United Kingdom
Germany
India

22 FDA-registered drug labelers

Advagen Pharma Ltd

Amneal Pharmaceuticals LLC

Baxter Healthcare Corporation

Cipla USA Inc.

Curia Italy S.r.l.

Gland Pharma Limited

Hikma Pharmaceuticals USA Inc.

Hovione FarmaCiencia SA

Impel Pharmaceuticals LLC

LETCO MEDICAL, LLC

Medisca Inc.

MIPHARM SPA

Oceanside Pharmaceuticals

Olon SpA

Professional Compounding Centers of America

Professional Compounding Centers of America dba PCCA

Provepharm Inc.

Satsuma Pharmaceuticals, Inc.

Somerset Therapeutics, LLC

TAPI Czech Industries s.r.o.

Teva Czech Industries s.r.o

Trifluent Pharma, LLC

Why It Matters

Sectors

Health

Downstream Uses

Appears in 5 drug and cosmetic product listings (FDA).

•Dihydroergotamine mesylate
•Trudhesa
•Atzumi
•Brekiya
•Dihydroergotamine Mesylate Nasal

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$344.00/gAstaTech, Inc

CountryUnited States

Pack$344.00 / 1 g

Purity95%

Vendors10 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

9 more vendors

Vendor	Country	$/g	Pack	Purity
Labotest KG	Germany	$453.00	1000 mg	90%
CliniSciences GmbH	Switzerland	$761.10	100 mg	98%
Sigma-Aldrich (Rush Stock)	Germany	$1044.16	500 mg	—
Sigma-Aldrich	Germany	$1044.16	500 mg	—
MedChemExpress MCE	Sweden	$1306.80	100 mg	99.94%
Molnova	China	$1380.00	50 mg	99%
MedKoo Biosciences, Inc	United States	$1450.00	1 g	98%
Cayman Europe	Estonia	$1570.80	250 mg	98%
Apexbio Technology LLC	United States	$2600.00	50 mg	—

Chemical Identity

CAS6190-39-2

PubChem CID71171

DTXSIDDTXSID00904615

FormulaC34H41N5O8S

Mol. Weight679.8 g/mol

SMILESCC1(C(=O)N2C(C(=O)N3CCCC3C2(O1)O)CC4=CC=CC=C4)NC(=O)C5CC6C(CC7=CNC8=CC=CC6=C78)N(C5)C.CS(=O)(=O)O

Data Sources

PubChem · compound 71171Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Dihydroergotamine mesylate (CAS 6190-39-2) https://chemicalindependence.com/chemical/6190-39-2/ PubChem: 71171. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/71171 FDA National Drug Code directory: CAS 6190-39-2. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293969 for CAS 6190-39-2. Reporting year: 2024. https://usatrade.census.gov/