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acetylcysteine

Drug ingredient

CAS 616-91-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 616-91-1
US productionNot reported
Import value, 2024$760M
Top sourceChina 33%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293090 · basket

These shares come from HS customs code 293090, which covers 418 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 33%ChinaES 14%SpainCH 9%SwitzerlandIT 7%ItalyIN 7%India
24 FDA-registered drug labelers
American Regent, Inc.
Cameron Pharmaceuticals
Cardinal Health 107, LLC
Cumberland Pharmaceuticals Inc.
Eugia US LLC
F.I.S. Fabbrica Italiana Sintetici S.P.A.
Fresenius Kabi USA, LLC
Fujian South Pharmaceutical Co., Ltd.
Glenmark Pharmaceuticals Inc., USA
Guna spa
Hikma Pharmaceuticals USA Inc.
Hospira, Inc.
Indoco Remedies Limited
Moehs Catalana SL
Nippon Rika Co., Ltd.
ONESOURCE SPECIALTY PHARMA LIMITED
Padagis US LLC
PharmaZell GmbH
Professional Compounding Centers of America dba PCCA
PureTek Corporation
Sagent Pharmaceuticals
Somerset Therapeutics, LLC
Spectrum Laboratory Products, Inc.
Xellia Pharmaceuticals USA LLC

Why It Matters

Sectors
Health
Downstream Uses

Appears in 4 drug and cosmetic product listings (FDA).

  • •Acetylcysteine
  • •ANTI AGE Stress
  • •Folcyteine
  • •Acetadote
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$3.36/gAA BLOCKS
CountryUnited States
Pack$84.00 / 25 g
Purity95%
Vendors18 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

17 more vendors
VendorCountry$/gPackPurity
A2B Chem LLCUnited States$3.3625 g95%
Aaron Chemicals LLCHong Kong$3.4425 g97%
Angene ChemicalChina → Hong Kong$3.4850 g97%
Ambeed, Inc.United States$4.2025 g97%
Combi-Blocks, Inc.United States$4.2025 g95%
BLD Pharmatech Ltd.China$4.6025 g97%
ChemsceneUnited States$5.0425 g—
Angene International LimitedUnited States$5.0825 g95%
BLD Pharmatech Co., LimitedUnited States$5.1010 g97%
BLD Pharmatech GmbHGermany$5.605 g97%
Fluorochem EUGermany$5.7625 g97%
Apexbio Technology LLCUnited States$6.6010 g99.51%
Fulfilled by MolportLatvia$40.00100 mg97%
AstaTech, IncUnited States$41.005 g95%
Life Chemicals Inc.Ukraine → Canada$72.00250 mg95%
Otava, Ltd. (2 weeks)Ukraine$2724.0050 mg90%
AngeneChina → Hong Kong$4266.6730 mg97%

Chemical Identity

CAS616-91-1
PubChem CID12035
DTXSIDDTXSID5020021
FormulaC5H9NO3S
Mol. Weight163.2 g/mol
SMILESCC(=O)NC(CS)C(=O)O

Data Sources

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Brief citations

acetylcysteine (CAS 616-91-1) https://chemicalindependence.com/chemical/616-91-1/ PubChem: 12035. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/12035 EPA TSCA Inventory: CAS 616-91-1. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293090 for CAS 616-91-1. Reporting year: 2024. https://usatrade.census.gov/