2-Pyrrolidinone
CAS 616-45-5
U.S. production volumes are classified as confidential business information.
At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.
Why supply is unknownProduction is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.
Where It Comes From
Customs basis: HS 293379 · basket
- 2023
- US production Confidential · Imports Confidential
- 2019
- US production Confidential · Imports Confidential
These shares come from HS customs code 293379, which covers 105 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.
- Brazil
- Canada
- Taiwan
- Ukraine
- Portugal
- Netherlands
- South Korea
- Israel
- Czech Republic
- Spain
- Finland
- Hungary
- Malaysia
- Australia
- Austria
- Slovenia
Why It Matters
Industrial Uses
Used in 3 sectors as 2 functional roles.
- •Intermediate in All Other Basic Organic Chemical Manufacturing (100%)Processing as a reactant
- •Solvent in Printing Ink Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Solvent in Mining (except Oil and Gas) and support activitiesProcessing—incorporation into formulation, mixture, or reaction product
Vendor Pricing
Prices reflect listed pack sizes. Small research packs run far above bulk rates.
15 more vendors
| Vendor | Country Supplier country. Where available, shows shipping origin. When the supplier ships from a different country than where they are registered, both are shown. Most suppliers show registration country only. | $/g | Pack | Purity |
|---|---|---|---|---|
| A2B Chem LLC | United States | $0.03 | 25 kg | 98% |
| Sigma-Aldrich (Rush Stock) | Germany | $0.07 | 18 kg | 99% |
| Sigma-Aldrich | Germany | $0.07 | 18 kg | 99% |
| ALFA AESAR | Germany | $0.07 | 2 kg | 99% |
| AK Scientific Specialized | United States | $0.10 | 500 g | 98% |
| AK Scientific, Inc. | United States | $0.13 | 500 g | 99.5% |
| AstaTech, Inc | United States | $0.23 | 250 g | 95% |
| Combi-Blocks, Inc. | United States | $0.25 | 1 kg | 98% |
| Apollo Scientific UK | United Kingdom | $2.40 | 25 g | 95% |
| Interbioscreen | Hong Kong | $10.00 | 10 g | 95% |
| Labotest KG | Germany | $217.80 | 5000 mg | 90% |
| Otava, Ltd. | Ukraine | $2280.00 | 50 mg | 95% |
| Otava, Ltd. (2 weeks) | Ukraine | $2724.00 | 50 mg | 90% |
| ChemDiv, Inc. | United States | $4070.00 | 100 mg | 90% |
| TimTec, LLC (back-ordered) | United States | $32000.00 | 15 mg | 94% |
Chemical Identity
Data Sources
- EPA CompTox (DSSTox) · DTXSID8027246Retrieved 2026-04-06
- PubChem · compound 12025Retrieved 2026-04-06
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
2-Pyrrolidinone (CAS 616-45-5) https://chemicalindependence.com/chemical/616-45-5/ EPA CompTox (DSSTox): DTXSID8027246. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID8027246 PubChem: 12025. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/12025 EPA Chemical Data Reporting: 616-45-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 616-45-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 293379 for CAS 616-45-5. Reporting year: 2024. https://usatrade.census.gov/