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Trehalose dihydrate

Drug ingredient

CAS 6138-23-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 6138-23-4
2 H₂O
US productionNot reported
Import value, 2024$189M
Top sourceChina 25%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 294000 · basket

These shares come from HS customs code 294000, which covers 41 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 25%ChinaDE 16%GermanyIT 11%ItalyCA 7%CanadaDK 7%Denmark
1 FDA-registered drug labeler
Avantor Performance Materials, LLC

Why It Matters

Sectors
Health
Downstream UsesNot recorded
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS6138-23-4
PubChem CID181978
DTXSIDDTXSID3047972
FormulaC12H26O13
Mol. Weight378.33 g/mol
SMILESC(C1C(C(C(C(O1)OC2C(C(C(C(O2)CO)O)O)O)O)O)O)O.O.O

Data Sources

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Brief citations

Trehalose dihydrate (CAS 6138-23-4) https://chemicalindependence.com/chemical/6138-23-4/ PubChem: 181978. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/181978 FDA National Drug Code directory: CAS 6138-23-4. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 294000 for CAS 6138-23-4. Reporting year: 2024. https://usatrade.census.gov/