phenylephrine hydrochloride

Drug ingredient

CAS 61-76-7

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 61-76-7
1 HCl
US productionNot reported
Import value, 2024$652M
Top sourceSingapore 77%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292250 · basket

These shares come from HS customs code 292250, which covers 76 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
SG 77%SingaporeCN 12%ChinaIT 4%ItalyIN 2%IndiaGB 1%United Kingdom
307 FDA-registered drug labelers
100 KARMA INC
A-S Medication Solutions
AAA PHARMACEUTICAL, INC.
Acme United
Acme United Corporation
ACTIPHARMA, LLC
Advanced Generic Corporation
Advanced Rx LLC
Alcon Laboratories, Inc.
Alera Skin Care Products Inc.
Allegiant Health
Allegis Pharmaceuticals, LLC
Alternative Pharmacal Corporation
AMAZON.COM SERVICES LLC
American Sales Company
AMERISOURCE BERGEN
AmerisourceBergen Drug Corp
Amerisourcebergen Drug Corporation
Amneal Pharmaceuticals LLC
APL HEALTHCARE LIMITED
AptaPharma Inc.
Armas Pharmaceuticals Inc.
Army & Air Force Exchange Service
ARMY AND AIR FORCE EXCHANGE SERVICE
Aurohealth LLC
AX Pharmaceutical Corp
Bausch & Lomb Americas Inc.
Bayer HealthCare LLC
BE Pharmaceuticals Inc.
Belmora LLC
BENARD INDUSTRIES INC
Best Choice
Best Choice (Valu Merchandisers Company)
BETTER LIVING BRANDS LLC
Beyond Health P.A.
BF ASCHER AND CO INC
BI-MART
Bionpharma Inc.
Bioventure Healthcare - FZE
Bliss GVS Pharma Limited
Blistex Inc.
Boehringer Ingelheim Pharma GmbH and Co. KG
BOWLER ESTHETICS, INC
Bryant Ranch Prepack
Cabinet Health P.B.C.
Camber Pharmaceuticals, Inc.
Capital Pharmaceutical, LLC
Caplin Steriles Limited
CARDINAL HEALTH
Cardinal Health (Leader) 70000
Cardinal Health 107, LLC
Cardinal Health 110 dba LEADER
CARDINAL HEALTH 110, LLC. DBA LEADER
CARDINAL HEALTH 110, LLC. DBA LEADER 70000
Care One (American Sales Company)
Care One (Retail Business Services, LLC.)
Catalent Ontario Limited
CHAIN DRUG CONSORTIUM
Chain Drug Consortium, LLC
Chain Drug Manufacturing Assn
CHAIN DRUG MARKETING ASSOCIATION
CHAIN DRUG MARKETING ASSOCIATION INC
Cheng Fong Chemical Co., Ltd.
Cintas Corporation
Civica, Inc.
Clinical Resolution Laboratory, Inc.
Crane Safety LLC
CVS
CVS HEALTH CORP
CVS PHARMACY
CVS PHARMACY, INC
CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED
DeMoulas Market Basket
Derma Care Research Labs
Derma Care Research Labs, LLC
Dextrum Laboratories Inc.
DISCOUNT DRUG MART
Divi's Laboratories Limited
DLC Laboratories, Inc.
Dolgencorp Inc
DOLGENCORP, INC. (DOLLAR GENERAL & REXALL)
DOLGENCORP, LLC
Domel Laboratories
DONGWHA PHARM. CO. LTD.
DORAL PHARMAMEDICS INC dba A.G. Marin Pharmaceuticals
Dr. Reddy's Laboratories Inc.
Ebanel Laboratories, Inc.
EDWARDS PHARMACEUTICALS, INC.
EFFICIENT LABORATORIES INC
ELIXIR HEALTHCARE USA, LLC.
ELYSIUM PHARMACEUTICALS LIMITED
Elysium Pharmaceuticals Ltd
EQUATE (Wal-Mart Stores, Inc.) (see also WAL-MART INC)
Eugia US LLC
EVER READY FIRST AID
Fagron Inc
FAMILY DOLLAR
FAMILY DOLLAR (Family Wellness)
FAMILY DOLLAR SERVICES
Family Dollar Services Inc
Ferndale Laboratories, Inc.
FloCal Distributors LLC
FOODHOLD U.S.A., LLC
FORTUNE PHARMACAL COMPANY LIMITED
Foundation Consumer Brands
FOURSTAR GROUP USA, INC.
Fresenius Kabi USA, LLC
FRONT PHARMACEUTICAL PLC
FSA Store Inc. (Caring Mills)
Geiss, Destin & Dunn Inc.
Genomma Lab USA
Genomma Lab USA, Inc
Genus Lifesciences Inc.
Gil Pharmaceutical Corp
Giltuss Pharmaceutical Corp
Gland Pharma Limited
Globela Pharma Pvt Ltd
GM Pharmaceuticals, INC
Gobrands, Inc. (Goodnow)
GOODSENSE
GRANDALL DISTRIBUTING, LLC
GRAXCELL PHARMACEUTICAL, LLC
Grocery Outlet
Grocery Outlet, Inc.
Guardian Drug Company
H E B
Hainan Poly Pharm. Co., Ltd.
Haleon US Holdings LLC
HARRIS TEETER
Harris Teeter, LLC
HART Health
Health Pharma USA LLC
HealthLife of USA
Henry Schein, Inc.
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.
HF Acquisition Co LLC, DBA HealthFirst
HHH PHARMA USA LLC
Hi-Tech Nutraceuticals, LLC
Hikma Pharmaceuticals USA Inc.
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5e0ef968-dff3-4446-8412-8085677332f0
Humanwell PuraCap Pharmaceutical (Wuhan) Co., Ltd
Humanwell PuraCap Pharmaceutical (Wuhan), Ltd.
HYVEE INC
Innovus Pharmaceuticals, Inc.
Inspec Solution LLC.
InvaTech Pharma Solutions LLC
Janssen Cilag SpA
JC World Bell Wholesale Co., Inc.
JHK DBA American Safety & First Aid
JHK Inc dba American Safety & First Aid
Jiangxi Yudexi Pharmaceutical Co., LTD
Jones Healthcare Group - Packaging Services, Inc
Kenvue Brands LLC
KinderFarms, LLC
KRAMER NOVIS
KROGER
KROGER COMPANY
L Perrigo Company
L.N.K. International, Inc.
LABORATORIO MAGNACHEM INTERNATIONAL SRL
LALANI Rx Consulting, Inc.
Larken Laboratories, Inc.
Leading Pharma, LLC
LETCO MEDICAL, LLC
Lidl US LLC
Lifestar Pharma LLC
Lil Drug Store Products, Inc
Little Pharma, Inc
Llorens Pharmaceutical International Division, Inc.
LLORENS PHARMACEUTICALS INTERNATIONAL DIVISION
MADISON ONE ACME INC
Major Pharmaceuticals
Malladi Drugs & Pharmaceuticals Limited
MARC GLASSMAN, INC.
McKesson Medical-Surgical
Medical Purchasing Solutions, LLC
Medical Purhasing Solutions, LLC
Medisca Inc.
MEDWISE LIFESCIENCES INC.
MEGABABE, LLC
Meijer
MEIJER DISTRIBUTION INC
MEIJER, INC.
Meitheal Pharmaceuticals Inc.
Menper Distributors, Inc
Method Pharmaceuticals, LLC
MIDWAY IMPORTING INC.
Mohnark Pharmaceuticals Inc
Morning Star OTC
Nantong Health & Beyond Hygienic Products Inc.
Navajo Manufacturing Company Inc.
NeilMed Pharmaceuticals Inc.
New World Imports, Inc
NorthStar RxLLC
Novadoz Pharmaceuticals LLC
NUVICARE LLC
Oakhurst Company
Okendpharma, Inc.
OL PHARMA TECH, LLC Drs PHARMACY
OPMX LLC
P & L Development, LLC
Padagis Israel Pharmaceuticals Ltd
Papalo Group LLC
Par Health USA, LLC
Paragon BioTeck, Inc.
Patheon Softgels Inc
Perrigo Direct, Inc
Pharmacy Value Alliance LLC
Pharmadel LLC
Pioneer Life Sciences, LLC
Poly Pharmaceuticals, Inc.
POPPY COLLECTIVE LLC
Preferred Pharmaceuticals Inc.
Prestige Brands Holdings, Inc.
Procaps S.A. de C.V.
Procter & Gamble Manufactura S de RL de CV
Procter & Gamble Manufacturing Company
Prodose, Inc.
Productos Farmaceuticos, S.A. de C.V.
Professional Compounding Centers of America dba PCCA
Proficient Rx LP
ProPharma Distribution
Provepharm Inc.
PUBLIX SUPER MARKETS INC
PuraCap Pharmaceutical LLC
QUALITY CHOICE (Chain Drug Marketing Association)
R J General Corporation
RANDOB LABS,LTD. DBA CROSSINGWELL CONSUMER HEALTH
RARITAN PHARMACEUTICALS
RARITAN PHARMACEUTICALS INC
RB Health (US)
RB Health (US) LLC
Redicare LLC
RETAIL BUSINESS SERVICES , LLC.
RITE AID
Rite Aid Corporation
Rnv LLC
Rugby
Rugby Laboratories
SAFEWAY
Safeway, Inc.
Sagent Pharmaceuticals
SALADO SALES INC.
Sandoz Inc
Sato Pharmaceutical Co., Ltd.
Selder, S.A. de C.V.
Shenzhen Oriental Pharmaceutical Co. Ltd.
Shield Pharmaceuticals Corp
SHILPA PHARMA LIFESCIENCES LIMITED
Siegfried PharmaChemikalien Minden GmbH
SIMPLE PROMISE PTE LTD
SOFTGEL HEALTHCARE PRIVATE LIMITED
Softgel Healthcare Pvt Ltd
SOLA Pharmaceuticals, LLC
Somerset Therapeutics, LLC
Spectrum Laboratory Products, Inc.
Spera Nexus, Inc.
Sportpharm LLC
Strategic Sourcing Services
STRATEGIC SOURCING SERVICES LLC
Strive Pharmaceuticals Inc.
SUPERVALU INC
Syn-Tech Chem. & Pharm. Co., Ltd.
TARGET CORP
TARGET CORPORATION
THE KROGER CO
The Kroger Company
The Procter & Gamble Manufacturing Company
Thompson
TIME CAP LABORATORIES, INC.
TINA DAVIES PROFESSIONAL LLC
TOP CARE (Topco Associates LLC)
TOPCARE
TOPCO ASSOCIATES LLC
Totally Normal Company
Trifecta Pharmaceuticals USA LLC
Trillium Health Care Products Inc.
TWIN MED, LLC
U.S. PHARMACEUTICAL CORPORATION
Ulai Health LLC
Unifirst First Aid Corporation
Unipack LLC
Unishield
United Exchange Corp
United Natural Foods, Inc. dba UNFI
Universal Distribution Center LLC
Valu Merch
VALU MERCHANDISERS COMPANY
Veridian Healthcare
VIVUNT PHARMA LLC
Vovantis Laboratories Private Limited
Wal-Mart Stores Inc
WALGREEN CO.
WALGREEN COMPANY
WALGREENS
WALGREENS CO
Walgreens Company
WALMART INC.
Westminster Pharmaceuticals, LLC
Wildman Business Group
Willow Birch Pharma, Inc.
WINCO FOODS, LLC
Xellia Pharmaceuticals USA LLC
YITONGBADA (SHENZHEN) INTERNATIONAL TRADE CO., LTD
YYBA CORP
Zhejiang Hisoar Chuannan Pharmaceutical Co., Ltd.
Zhejiang Jingwei Pharmaceutical Co., Ltd.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 932 drug and cosmetic product listings (FDA).

  • •Acetaminophen 325 mg, Dextromethorphan Hydrobromide 10 mg, Phenlyephrine Hydrochloride 5 mg softgel (DAY-TIME)
  • •Phenylephrine Hydrochloride
  • •Sinus Pressure plus Pain PE
  • •Sinus Sevre
  • •Allergy MultiSymptom
  • •Numb520Spray
  • •DCH Hemorrhoidal
  • •Revivol Hemorrhoid and Fissure
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS61-76-7
PubChem CID5284443
DTXSIDDTXSID3021142
FormulaC9H14ClNO2
Mol. Weight203.66 g/mol
SMILESCNCC(C1=CC(=CC=C1)O)O.Cl

Data Sources

Brief citations

phenylephrine hydrochloride (CAS 61-76-7) https://chemicalindependence.com/chemical/61-76-7/ PubChem: 5284443. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5284443 EPA TSCA Inventory: CAS 61-76-7. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 292250 for CAS 61-76-7. Reporting year: 2024. https://usatrade.census.gov/