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methylene blue

Drug ingredient

CAS 61-73-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 61-73-4
1 Cl⁻
US productionNot reported
Import value, 2024$24M
Top sourceIndia 35%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 320413 · basket

These shares come from HS customs code 320413, which covers 64 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IN 35%IndiaMX 27%MexicoDE 16%GermanyTW 3%TaiwanCN 3%China
40 FDA-registered drug labelers
Aktinos pharma Private Limited
Allegis Pharmaceuticals, LLC
American Regent, Inc.
Amneal Pharmaceuticals LLC
Azico Biophore India Private Limited
Beijing JUNGE Technology Co., Ltd.
BILLS BIOTECH PRIVATE LIMITED
BPI LABS LLC
Chengdu Shuode Pharmaceutical Co., Ltd
Cohance Lifesciences Limited
Cutyx Research LLP
DARMERICA, LLC
DORAL PHARMAMEDICS INC dba A.G. Marin Pharmaceuticals
EDWARDS PHARMACEUTICALS, INC.
Fast Sold LLC
Guna spa
Hikma Pharmaceuticals USA Inc.
KALCHEM INTERNATIONAL INC
KALINTIS HEALTHCARE PRIVATE LIMITED
LETCO MEDICAL, LLC
MACSEN DRUGS
Medisca Inc.
Meitheal Pharmaceuticals Inc.
Method Pharmaceuticals, LLC
Mission Pharmacal Company
Nexus Pharmaceuticals, LLC
NuCare Pharmaceuticals,Inc.
Nucleic Products, LLC
PharmaZell GmbH
PROFESSIONAL COMPOUNDING CENTERS OF AMERICA
SCH Global Services Private Limited
Shandong Keyuan Pharmaceutical Co.,Ltd.
SHOOLIN PHARMA CHEM LLP
Sichuan Qingmu Pharmaceutical Co., Ltd.
Steriscience Specialties Private Limited
Tianjin Weijie Pharmaceutical Co. Ltd.
Viatris Specialty LLC
XIROMED, LLC
Zydus Lifesciences Limited
Zydus Pharmaceuticals USA Inc.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 13 drug and cosmetic product listings (FDA).

  • •Methylene blue
  • •Arthcal 1% Methylene BLUE
  • •Provayblue
  • •Uribel TABS
  • •Celltem
  • •GUNA-Kidney
  • •Urimar-T CAPS
  • •Urogesic BLUE
Show all 13
  • •Uretron D/S
  • •Ozipco 1% Methylene BLUE
  • •Uro-MP
  • •MB CAPS
  • •Urelle
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$0.07/gAaron Chemicals LLC
CountryHong Kong
Pack$327.00 / 5 kg
Purity98%
Vendors19 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

18 more vendors
VendorCountry$/gPackPurity
Angene ChemicalChina → Hong Kong$0.10500 g98%
A2B Chem LLCUnited States$0.14500 g98%
AA BLOCKSUnited States$0.16500 g—
BLD Pharmatech Co., LimitedUnited States$0.191 kg95%
BLD Pharmatech GmbHGermany$0.191 kg95%
Ambeed, Inc.United States$0.191 kg95%
AK Scientific SpecializedUnited States$0.201 kg95%
Fluorochem EUGermany$0.23100 g70%
Combi-Blocks, Inc.United States$0.251 kg97%
AK Scientific, Inc.United States$0.261 kg97%
Fluorochem UKUnited Kingdom$0.37100 g95%
AstaTech, IncUnited States$0.8825 g95%
Angene International LimitedUnited States$0.9225 g98%
MedChemExpress MCESweden$2.43100 g95%
MedKoo Biosciences, IncUnited States$7.50100 g98%
Labotest KGGermany$217.805000 mg90%
AngeneChina → Hong Kong$4266.6730 mg98%
Key Organics Ltd.United Kingdom$6900.0010 mg95%

Chemical Identity

CAS61-73-4
PubChem CID6099
DTXSIDDTXSID0023296
FormulaC16H18ClN3S
Mol. Weight319.9 g/mol
SMILESCN(C)C1=CC2=C(C=C1)N=C3C=CC(=[N+](C)C)C=C3S2.[Cl-]

Data Sources

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Brief citations

methylene blue (CAS 61-73-4) https://chemicalindependence.com/chemical/61-73-4/ PubChem: 6099. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/6099 EPA TSCA Inventory: CAS 61-73-4. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 320413 for CAS 61-73-4. Reporting year: 2024. https://usatrade.census.gov/