Apremilast

Drug ingredient

CAS 608141-41-9

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 608141-41-9
US productionNot reported
Import value, 2024$760M
Top sourceChina 33%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293090 · basket

These shares come from HS customs code 293090, which covers 418 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 33%ChinaES 14%SpainCH 9%SwitzerlandIT 7%ItalyIN 7%India
19 FDA-registered drug labelers
Amgen, Inc
Aurobindo Pharma Limited
AX Pharmaceutical Corp
Dr.Reddy's Laboratories Limited
Hainan Poly Pharm. Co., Ltd.
Hetero Drugs Limited
Jubilant Biosys limited
Lonza AG
Lonza Bend Inc
MSN Life Sciences Private Limited
Neuland Laboratories Limited
Patheon Inc.
Pharmaceutical Works POLPHARMA
Pliva Croatia Ltd
Quimica Sintetica S.A.
ScinoPharm Taiwan Ltd.
SUN PHARMACEUTICAL INDUSTRIES, INC.
Unichem Laboratories Limited, India
Zhejiang Huahai Pharmaceutical Co., Ltd.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

  • •Otezla
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$4.92/gAaron Chemicals LLC
CountryHong Kong
Pack$123.00 / 25 g
Purity98%
Vendors26 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS608141-41-9
PubChem CID11561674
DTXSIDDTXSID30976289
FormulaC22H24N2O7S
Mol. Weight460.5 g/mol
SMILESCCOC1=C(C=CC(=C1)C(CS(=O)(=O)C)N2C(=O)C3=C(C2=O)C(=CC=C3)NC(=O)C)OC

Data Sources

Brief citations

Apremilast (CAS 608141-41-9) https://chemicalindependence.com/chemical/608141-41-9/ PubChem: 11561674. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/11561674 FDA National Drug Code directory: CAS 608141-41-9. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293090 for CAS 608141-41-9. Reporting year: 2024. https://usatrade.census.gov/