binimetinib

Drug ingredient

CAS 606143-89-9

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 606143-89-9
US productionNot reported
Import value, 2024$1.4B
Top sourceIreland 33%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293399 · basket

These shares come from HS customs code 293399, which covers 518 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 33%IrelandCN 26%ChinaIN 11%IndiaDE 9%GermanyIT 4%Italy
3 FDA-registered drug labelers
Array BioPharma Inc.
MSN Laboratories Private Limited
Valary Lab Private Limited

Why It Matters

Sectors
Health
Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

  • •Mektovi
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$600.00/gExcenen Pharmatech Co., Ltd
CountryChina
Pack$600.00 / 1 g
Purity98%
Vendors21 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS606143-89-9
PubChem CID10288191
DTXSIDDTXSID70209422
FormulaC17H15BrF2N4O3
Mol. Weight441.2 g/mol
SMILESCN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)F)C(=O)NOCCO

Data Sources

Brief citations

binimetinib (CAS 606143-89-9) https://chemicalindependence.com/chemical/606143-89-9/ PubChem: 10288191. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/10288191 FDA National Drug Code directory: CAS 606143-89-9. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293399 for CAS 606143-89-9. Reporting year: 2024. https://usatrade.census.gov/