Phlorizin

Drug ingredient

CAS 60-81-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$296M

Top sourceChina 71%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293890 · basket

These shares come from HS customs code 293890, which covers 25 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 71%ChinaMY 11%MalaysiaBR 3%BrazilKR 2%South KoreaCL 2%Chile

United Kingdom
Canada
Guatemala
Bulgaria
New Zealand
Thailand
Turkey
Belgium
Sweden
Netherlands
Austria
Israel
Mexico
Australia
Ecuador
Finland
Slovakia
Hong Kong
Romania
Colombia
Taiwan

5 FDA-registered drug labelers

Deseret Biologicals, Inc.

Dr. Donna Restivo DC

Energetix Corporation

Energique, Inc.

Professional Complementary Health Formulas

Why It Matters

Sectors

Health

Downstream Uses

Appears in 6 drug and cosmetic product listings (FDA).

•Glucoreg
•Isopathic Phenolic Rings
•Phloridzin Phenolic
•Multi-Phenolic
•Sugar Cravings
•Phloridzin 1535

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS60-81-1

PubChem CID6072

DTXSIDDTXSID3075339

FormulaC21H24O10

Mol. Weight436.4 g/mol

SMILESC1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2OC3C(C(C(C(O3)CO)O)O)O)O)O)O

Data Sources

PubChem · compound 6072Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Phlorizin (CAS 60-81-1) https://chemicalindependence.com/chemical/60-81-1/ PubChem: 6072. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/6072 FDA National Drug Code directory: CAS 60-81-1. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293890 for CAS 60-81-1. Reporting year: 2024. https://usatrade.census.gov/