Diethyl ether

Drug ingredient

CAS 60-29-7

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$7M

Top sourceIndia 40%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023.

Where It Comes From

Customs basis: HS 290911 · exact

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

Source Countries

Country of origin for US imports, from Census customs data (2024).

IN 40%IndiaMX 37%MexicoDE 21%GermanyCN 1%China

South Korea
Switzerland
Italy

EPA-registered manufacturers (2)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Ashland

International Flavors And Fragrances

Domestic parents -- activity not disclosed (2)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Lyondell Chemical

Tedia

EPA-registered importers (4)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Bae Systems

Honeywell International (123312)

Thermo Fisher Scientific

W. R. Grace & Co. - Conn.

Why It Matters

Sectors

HealthDefenseMetals & MiningConsumer ProductsCore Chemicals

Downstream Uses

Appears in 3 drug and cosmetic product listings (FDA).

•Etherum
•Pan-Zyme-S
•N02 Petrochem

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 7 sectors as 4 functional roles.

•Solvent in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Freeze-thaw additive in Other (100%)Processing—repackaging
•Solvent in Explosives Manufacturing (100%)Use—non-incorporative activities
•Laboratory chemicals in All Other Basic Organic Chemical ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
•Laboratory chemicals in Wholesale and Retail TradeNot Known or Reasonably Ascertainable
•Intermediate in Pharmaceutical and Medicine ManufacturingNot Known or Reasonably Ascertainable
•Laboratory chemicals in ServicesNot Known or Reasonably Ascertainable

Chemical Identity

CAS60-29-7

PubChem CID3283

DTXSIDDTXSID3021720

FormulaC4H10O

Mol. Weight74.12 g/mol

SMILESCCOCC

Data Sources

EPA CompTox (DSSTox) · DTXSID3021720Retrieved 2026-04-06
PubChem · compound 3283Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Diethyl ether (CAS 60-29-7) https://chemicalindependence.com/chemical/60-29-7/ EPA CompTox (DSSTox): DTXSID3021720. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID3021720 PubChem: 3283. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/3283 EPA Chemical Data Reporting: 60-29-7. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 60-29-7. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 290911 for CAS 60-29-7. Reporting year: 2024. https://usatrade.census.gov/