Creatinine

Drug ingredient

CAS 60-27-5

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$114M

Top sourceChina 26%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293329 · basket

These shares come from HS customs code 293329, which covers 173 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 26%ChinaIN 17%IndiaKR 16%South KoreaDE 9%GermanyIT 9%Italy

Australia
Brazil
Czech Republic
Ireland
Sweden
Ukraine
Poland
United Arab Emirates
Hungary
Israel
Netherlands
Canada
Saudi Arabia
Greece
Belgium
Austria
Latvia
Singapore
Denmark

1 FDA-registered drug labeler

BioActive Nutritional, Inc.

Why It Matters

Sectors

Health

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•Colotox

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$0.06/gAaron Chemicals LLC

CountryHong Kong

Pack$622.00 / 10 kg

Purity98%

Vendors23 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

22 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.07	1 kg	98%
A2B Chem LLC	United States	$0.08	1 kg	97%
AA BLOCKS	United States	$0.09	1 kg	98%
BLD Pharmatech GmbH	Germany	$0.11	1 kg	98%
BLD Pharmatech Ltd.	China	$0.11	1 kg	98%
BLD Pharmatech Co., Limited	United States	$0.12	1 kg	98%
Ambeed, Inc.	United States	$0.12	1 kg	98%
Combi-Blocks, Inc.	United States	$0.25	1 kg	97%
AK Scientific Specialized	United States	$0.25	500 g	95%
AK Scientific, Inc.	United States	$0.35	500 g	99%
Apollo Scientific UK	United Kingdom	$0.45	100 g	97%
Angene International Limited	United States	$0.61	500 g	98%
Sigma-Aldrich (Rush Stock)	Germany	$0.94	1 kg	98%
Sigma-Aldrich	Germany	$0.94	1 kg	98%
Cayman Europe	Estonia	$1.04	500 g	95%
Apexbio Technology LLC	United States	$14.00	5 g	99.54%
MedChemExpress MCE	Sweden	$17.91	5 g	99.92%
TargetMol Chemicals	China → United States	$50.00	1 g	99.36%
Specs	Netherlands	$1694.00	10 mg	90%
Otava, Ltd. (2 weeks)	Ukraine	$2724.00	50 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	98%
Key Organics Ltd.	United Kingdom	$6900.00	10 mg	98%

Chemical Identity

CAS60-27-5

PubChem CID588

DTXSIDDTXSID8045987

FormulaC4H7N3O

Mol. Weight113.12 g/mol

SMILESCN1CC(=O)N=C1N

Data Sources

PubChem · compound 588Retrieved 2026-04-07
EPA TSCA InventoryRetrieved 2026-04-24
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Creatinine (CAS 60-27-5) https://chemicalindependence.com/chemical/60-27-5/ PubChem: 588. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/588 EPA TSCA Inventory: CAS 60-27-5. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293329 for CAS 60-27-5. Reporting year: 2024. https://usatrade.census.gov/