D-Limonene

Drug ingredient

CAS 5989-27-5

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$90M

Top sourceJapan 21%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 290219 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 290219, which covers 108 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

JP 21%JapanBR 12%BrazilTW 12%TaiwanKR 11%South KoreaDE 9%Germany

Russia
United Kingdom
Indonesia
South Africa
Ukraine
Madagascar
Hungary
Hong Kong
Czech Republic
Israel

EPA-registered manufacturers (7)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Symrise Ag · DE Germany

Archer Daniels Midland

Brenntag

Brulin Holding

Florachem

Show all 7

Minerals Technologies

Symrise

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Reckitt Benckiser

EPA-registered importers (9)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Berje

Colgate-Palmolive

Henkel Us Operations

International Flavors And Fragrances

Kemira Water Solutions

Show all 9

Nalco- An Ecolab

P&G

S.C. Johnson & Son

The Sherwin Williams

Why It Matters

Sectors

HealthFoodEnergyConstructionPlastics & RubberConsumer ProductsPaper & PrintingCore Chemicals

Downstream Uses

Appears in 8 drug and cosmetic product listings (FDA).

•Anubis Barcelona Regul Oil
•Anubis Barcelona New Even
•Anubis Barcelona
•Purifying S.O.S spotgel
•Purifying centella soothing mask
•Puritying Skin BalanceCream
•Purifying Balance Soothing Peeling Pad
•Anubis Barcelona Vital Line

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 11 sectors as 5 functional roles.

•Fragrance in Plastics Material and Resin Manufacturing (1%)Processing—incorporation into article
•Fragrance in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (1%)Processing—incorporation into formulation, mixture, or reaction product
•Fragrance in All Other Chemical Product and Preparation Manufacturing (98%)Processing—incorporation into formulation, mixture, or reaction product
•Fragrance in Not Known or Reasonably Ascertainable (100%)Not Known or Reasonably Ascertainable
•Solvent in Furniture and Related Product Manufacturing (0%)Use—non-incorporative activities
•Solvent in Wood Product Manufacturing (0%)Use—non-incorporative activities
•Intermediate in All Other Chemical Product and Preparation Manufacturing (100%)Processing as a reactant
•Fragrance in Wholesale and Retail Trade (100%)Processing—incorporation into formulation, mixture, or reaction product
•Stabilizing agent in Non-metallic Mineral Product Manufacturing (includes clay, glass, cement, concrete, lime, gypsum, and other non-metallic mineral product manufacturing) (100%)Processing—incorporation into article
•Cleaning agent in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
•Intermediate in All Other Basic Organic Chemical Manufacturing (100%)Processing as a reactant
•Fragrance in Food, beverage, and tobacco product manufacturingProcessing—incorporation into formulation, mixture, or reaction product
•Cleaning agent in Oil and Gas Drilling, Extraction, and Support activitiesProcessing—incorporation into formulation, mixture, or reaction product

Chemical Identity

CAS5989-27-5

PubChem CID440917

DTXSIDDTXSID1020778

FormulaC10H16

Mol. Weight136.23 g/mol

SMILESCC1=CCC(CC1)C(=C)C

Data Sources

EPA CompTox (DSSTox) · DTXSID1020778Retrieved 2026-04-06
PubChem · compound 440917Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

D-Limonene (CAS 5989-27-5) https://chemicalindependence.com/chemical/5989-27-5/ EPA CompTox (DSSTox): DTXSID1020778. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID1020778 PubChem: 440917. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/440917 EPA Chemical Data Reporting: 5989-27-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 5989-27-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 290219 for CAS 5989-27-5. Reporting year: 2024. https://usatrade.census.gov/