Megestrol acetate

Drug ingredient

CAS 595-33-5

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 595-33-5
US productionNot reported
Import value, 2024$76M
Top sourceSpain 35%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293723 · basket

These shares come from HS customs code 293723, which covers 29 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
ES 35%SpainNL 19%NetherlandsCN 18%ChinaIT 16%ItalyHU 4%Hungary
22 FDA-registered drug labelers
American Health Packaging
ANI Pharmaceuticals, Inc.
ATLANTIC BIOLOGICALS CORP.
Bryant Ranch Prepack
Farmabios S.p.A.
Golden State Medical Supply, Inc.
Kesin Pharma Corporation
MAEDA INC
Major Pharmaceuticals
Natco Pharma USA LLC
PAI Holdings, LLC dba PAI Pharma
Pharmacia and Upjohn Company LLC
Precision Dose Inc.
Preferred Pharmaceuticals Inc.
PROFESSIONAL GROUP OF PHARMACISTS NEW YORK LLC
Proficient Rx LP
Sicor de Mexico S.A. de C.V
Strides Pharma Science Limited
Teva Pharmaceuticals USA, Inc.
Upsher-Smith Laboratories, LLC
Xttrium Laboratories, Inc.
Zhejiang Xianju Pharmaceutical Co., Ltd.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

  • •Megestrol Acetate
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$3.72/gAaron Chemicals LLC
CountryHong Kong
Pack$93.00 / 25 g
Purity98%
Vendors22 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS595-33-5
PubChem CID11683
DTXSIDDTXSID9040683
FormulaC24H32O4
Mol. Weight384.5 g/mol
SMILESCC1=CC2C(CCC3(C2CCC3(C(=O)C)OC(=O)C)C)C4(C1=CC(=O)CC4)C

Data Sources

Brief citations

Megestrol acetate (CAS 595-33-5) https://chemicalindependence.com/chemical/595-33-5/ PubChem: 11683. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/11683 FDA National Drug Code directory: CAS 595-33-5. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293723 for CAS 595-33-5. Reporting year: 2024. https://usatrade.census.gov/