Tafamidis

Drug ingredient

CAS 594839-88-0

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 594839-88-0
US productionNot reported
Import value, 2024$6.4B
Top sourceSingapore 36%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293499 · basket

These shares come from HS customs code 293499, which covers 575 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
SG 36%SingaporeIE 23%IrelandCN 11%ChinaCH 6%SwitzerlandIN 5%India
12 FDA-registered drug labelers
Alivus Life Sciences Limited
Aurobindo Pharma Limited
Biophore India Pharmaceuticals Pvt. Ltd
Catalent Micron Technologies, Inc.
Catalent Pharma Solutions, LLC
MSN Laboratories Private Limited
Neuland Laboratories Limited
NURAY CHEMICALS PRIVATE LIMITED
Pfizer Asia Manufacturing Pte Ltd
Pfizer Ireland Pharmaceuticals Unlimited Company
Pfizer Laboratories Div Pfizer Inc
TAPI Croatia Industries Ltd.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

  • •Vyndamax
FDA Shortage Status
No Shortage
Shortage History
  • to be discontinued

    Tafamidis Meglumine Capsule

    Shortage listed since September 29, 2025

See all current drug shortages

Vendor Pricing

$27.60/gAaron Chemicals LLC
CountryHong Kong
Pack$138.00 / 5 g
Purity98%
Vendors20 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS594839-88-0
PubChem CID11001318
DTXSIDDTXSID00208185
FormulaC14H7Cl2NO3
Mol. Weight308.1 g/mol
SMILESC1=CC2=C(C=C1C(=O)O)OC(=N2)C3=CC(=CC(=C3)Cl)Cl

Data Sources

Brief citations

Tafamidis (CAS 594839-88-0) https://chemicalindependence.com/chemical/594839-88-0/ PubChem: 11001318. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/11001318 FDA National Drug Code directory: CAS 594839-88-0. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 594839-88-0. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293499 for CAS 594839-88-0. Reporting year: 2024. https://usatrade.census.gov/