histidine monohydrochloride monohydrate

Drug ingredient

CAS 5934-29-2

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 5934-29-2 — 1 H₂O · 1 HCl

US productionNot reported

Import value, 2024$114M

Top sourceChina 26%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293329 · basket

These shares come from HS customs code 293329, which covers 173 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 26%ChinaIN 17%IndiaKR 16%South KoreaDE 9%GermanyIT 9%Italy

Australia
Brazil
Czech Republic
Ireland
Sweden
Ukraine
Poland
United Arab Emirates
Hungary
Israel
Netherlands
Canada
Saudi Arabia
Greece
Belgium
Austria
Latvia
Singapore
Denmark

2 FDA-registered drug labelers

Ajinomoto Health & Nutrition North America Inc.

Spectrum Laboratory Products, Inc.

Why It Matters

Sectors

Health

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$0.16/gAK Scientific Specialized

CountryUnited States

Pack$158.00 / 1 kg

Purity95%

Vendors14 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

13 more vendors

Vendor	Country	$/g	Pack	Purity
AK Scientific, Inc.	United States	$0.21	1 kg	99%
A2B Chem LLC	United States	$0.56	25 g	99%
Aaron Chemicals LLC	Hong Kong	$0.62	500 g	97%
Angene Chemical	China → Hong Kong	$0.67	500 g	98%
AA BLOCKS	United States	$0.68	25 g	97%
Combi-Blocks, Inc.	United States	$0.73	100 g	98%
BLD Pharmatech Ltd.	China	$1.39	500 g	97%
BLD Pharmatech Co., Limited	United States	$1.39	100 g	97%
BLD Pharmatech GmbH	Germany	$1.39	100 g	97%
Ambeed, Inc.	United States	$1.39	100 g	97%
Otava, Ltd.	Ukraine	$20.00	50 mg	95%
TargetMol Chemicals	China → United States	$78.00	500 mg	99.87%
Angene	China → Hong Kong	$4266.67	30 mg	97%

Chemical Identity

CAS5934-29-2

PubChem CID165377

DTXSIDDTXSID00208089

FormulaC6H12ClN3O3

Mol. Weight209.63 g/mol

SMILESC1=C(NC=N1)CC(C(=O)O)N.O.Cl

Data Sources

PubChem · compound 165377Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

histidine monohydrochloride monohydrate (CAS 5934-29-2) https://chemicalindependence.com/chemical/5934-29-2/ PubChem: 165377. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/165377 FDA National Drug Code directory: CAS 5934-29-2. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293329 for CAS 5934-29-2. Reporting year: 2024. https://usatrade.census.gov/