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Misoprostol

Drug ingredient

CAS 59122-46-2

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 59122-46-2
US productionNot reported
Import value, 2024$28M
Top sourceItaly 33%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293750 · basket

These shares come from HS customs code 293750, which covers 11 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IT 33%ItalyTW 27%TaiwanKR 14%South KoreaHU 13%HungaryGB 4%United Kingdom
32 FDA-registered drug labelers
Actavis Pharma, Inc.
Advanced Rx Pharmacy of Tennessee, LLC
American Health Packaging
Amneal Pharmaceuticals LLC
ANI Pharmaceuticals, Inc.
AvKARE
AvPAK
BluePoint Laboratories
Bryant Ranch Prepack
Cardinal Health 107, LLC
Chirogate International Inc
Everlight Chemical Industrial Corporation Kuanyin II Plant
GenBioPro, Inc.
Guangzhou Qiexiran Cosmetics Co., Ltd.
Kalchem International inc
LETCO MEDICAL, LLC
Lupin Pharmaceuticals,Inc.
Medisca Inc.
Micro Labs Limited
Mylan Pharmaceuticals Inc.
Nivagen Pharmaceuticals, Inc.
Novel Laboratories, Inc.
NuCare Pharmaceuticals, Inc.
PD-Rx Pharmaceuticals, Inc.
Pfizer Laboratories Div Pfizer Inc
PharmPak, Inc.
Piramal Healthcare UK Limited
Professional Compounding Centers of America
Proficient Rx LP
Redpharm Drug
Sportpharm LLC
YS Life Science Co., Ltd.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 9 drug and cosmetic product listings (FDA).

  • •Diclofenac Sodium Misoprostol
  • •Diclofenac Sodium/Misoprostol Diclofenac-Sodium-Misoprostol
  • •Misoprostol
  • •Diclofenac Sodium and Misoprostol
  • •Cytotec
  • •Arthrotec
  • •Diclofenac sodium and Misoprostol DR
  • •Tobcharm Toenail Fungus Treatment Liquid
Show all 9
  • •Dicloenac Sodium and Misoprostol DR
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS59122-46-2
PubChem CID5282381
DTXSIDDTXSID7020897
FormulaC22H38O5
Mol. Weight382.5 g/mol
SMILESCCCCC(C)(CC=CC1C(CC(=O)C1CCCCCCC(=O)OC)O)O

Data Sources

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Brief citations

Misoprostol (CAS 59122-46-2) https://chemicalindependence.com/chemical/59122-46-2/ PubChem: 5282381. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5282381 FDA National Drug Code directory: CAS 59122-46-2. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293750 for CAS 59122-46-2. Reporting year: 2024. https://usatrade.census.gov/