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Levodopa

Drug ingredient

CAS 59-92-7

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 59-92-7
US productionNot reported
Import value, 2024$652M
Top sourceSingapore 77%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292250 · basket

These shares come from HS customs code 292250, which covers 76 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
SG 77%SingaporeCN 12%ChinaIT 4%ItalyIN 2%IndiaGB 1%United Kingdom
62 FDA-registered drug labelers
A-S Medication Solutions
AbbVie Inc.
Accord Healthcare, Inc.
Actavis Pharma, Inc.
Advagen Pharma Ltd
Ajinomoto Co., Inc.
Alembic Pharmaceuticals Inc.
Alembic Pharmaceuticals Limited
American Health Packaging
Amneal Pharmaceuticals LLC
Amneal Pharmaceuticals NY LLC
Aphena Pharma Solutions - Tennessee, LLC
Aurobindo Pharma Limited
Avion Pharmaceuticals, LLC
AvKARE
BioActive Nutritional, Inc.
Bryant Ranch Prepack
Camber Pharmaceuticals, Inc.
Cardinal Health 107, LLC
Catalent Pharma Solutions, LLC
Coupler LLC
Deseret Biologicals
Deseret Biologicals, Inc
Divi's Laboratories Limited
Dr. Donna Restivo DC
Dr. Reddy's Laboratories Inc
Energique, Inc.
Engergique, Inc.
Guangzhou Renuma Medical Systems Co., Ltd
Hetero Drugs Limited
Macleods Pharmaceuticals Limited
Maithri Drugs Private Limited
Major Pharmaceuticals
Mayne Pharma International Pty Ltd
Merz Pharmaceuticals, LLC
MSN Life Sciences Private Limited
Mylan Institutional Inc.
Mylan Pharmaceuticals Inc.
NCS HealthCare of KY, LLC dba Vangard Labs
NuCare Pharmaceuticals,Inc.
Organon LLC
Orion Corporation, Orion Pharma
Pain & Stress Center Products
Professional Complementary Health Formulas
Professional Compounding Centers of America dba PCCA
Proficient Rx LP
Radha Pharmaceuticals Inc
Rising Pharma Holdings, Inc.
Safecor Health, LLC
Sandoz Inc
Savio Industrial SRL
ScieGen Pharmaceuticals Inc
Shandong Xinhua Pharmaceutical Company Limited
Spectrum Laboratory Products, Inc.
Sun Pharmaceutical Industries, Inc.
Teva Pharmaceutical Works Private Limited Company
Teva Pharmaceuticals USA, Inc.
TruPharma, LLC
Westminster Pharmaceuticals, LLC
XLCare Pharmaceuticals, Inc.
ZHEJIANG HUAHAI PHARMACEUTICAL CO., LTD.
Zydus Pharmaceuticals USA Inc.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 24 drug and cosmetic product listings (FDA).

  • •Carbidopa-levodopa
  • •Neuro-Pro T007
  • •Sinemet
  • •Carbidopa, Levodopa, and Entacapone
  • •Carbidopa and levodopa
  • •Young Again
  • •Rytary
  • •L-Dopa 1514
Show all 24
  • •Crexont
  • •HGH Vitality
  • •High Vitality Tab
  • •L DOPA 4X
  • •Neuro I
  • •Bio Thalamus Phase
  • •Dhivy
  • •Inbrija
  • •L-Dopa
  • •High Vitality
  • •Spectric
  • •Focus Spectrum HP
  • •L-Dopa Phenolic
  • •Multi-Phenolic
  • •Duopa
  • •Neuro Links
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS59-92-7
PubChem CID6047
DTXSIDDTXSID9023209
FormulaC9H11NO4
Mol. Weight197.19 g/mol
SMILESC1=CC(=C(C=C1CC(C(=O)O)N)O)O

Data Sources

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Brief citations

Levodopa (CAS 59-92-7) https://chemicalindependence.com/chemical/59-92-7/ PubChem: 6047. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/6047 EPA TSCA Inventory: CAS 59-92-7. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 292250 for CAS 59-92-7. Reporting year: 2024. https://usatrade.census.gov/