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Nicotinic acid

Drug ingredient

CAS 59-67-6

Companies reported imports and no US production of this drug ingredient to EPA for 2023.

Molecular structure of 59-67-6
US productionZero
Import value, 2024$295M
Import volume235.0K lb
Import dependency100%
Top sourceChina 56%

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Nicotinic acid · US import value by year
$154M2013$295M2024$305M2025

2013: $154M · 2024: $295M · Peak 2025: $305M

Where It Comes From

Customs basis: HS 293629 · basket

EPA reports by year
2023
US production Zero · Imports 235.0K lb
2019
US production Confidential · Imports Confidential

These shares come from HS customs code 293629, which covers 17 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 56%ChinaCH 12%SwitzerlandIN 12%IndiaIT 11%ItalyJP 2%Japan
EPA-registered importers (2)
Jubilant Ingrevia · IN India
Jubilant Life Sciences Usa

Why It Matters

Sectors
HealthFoodMetals & Mining
Downstream Uses

Appears in 30 drug and cosmetic product listings (FDA).

  • •Niacor
  • •Kidney Repair Center
  • •Niacin
  • •Integra Plus
  • •Multivitamin with Fluoride
  • •Davimet-M
  • •B-Balance Liquescence 3003
  • •Circulation
Show all 30
  • •Vitafol One
  • •GUNA-Liver
  • •Concept OB
  • •M-Natal Plus
  • •GUNA-Digest
  • •D-87
  • •A11 Enviro-Protect
  • •Vita-Rx Diabetic Vitamin
  • •TriStart DHA
  • •Circulation Drops 2013
  • •GUNA-CELL
  • •Davimet
  • •Integra F
  • •Davimet with Fluoride
  • •Methylation Assist Liquescence
  • •Melatonin Forte
  • •GUNA-Bowel
  • •Concept DHA
  • •SAMe Liquescence 3036
  • •JBA Collagen-Electrolyte Mocktail
  • •Multivitamin
  • •Diatrol
FDA Shortage Status
No FDA shortage records

Industrial Uses

Used in 3 sectors as 2 functional roles.

  • •Intermediate in Pharmaceutical and Medicine Manufacturing (20%)Processing—incorporation into formulation, mixture, or reaction product
  • •Flavoring and nutrient in Food, beverage, and tobacco product manufacturing (40%)Processing—incorporation into formulation, mixture, or reaction product
  • •Flavoring and nutrient in Other (40%)Processing—incorporation into formulation, mixture, or reaction product

Vendor Pricing

$0.01/gAaron Chemicals LLC
CountryHong Kong
Pack$75.00 / 5 kg
Purity98%
Vendors39 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

38 more vendors
VendorCountry$/gPackPurity
Angene ChemicalChina → Hong Kong$0.021 kg98%
BLD Pharmatech GmbHGermany$0.041 kg98%
BLD Pharmatech Ltd.China$0.041 kg98%
Fluorochem UKUnited Kingdom$0.051 kg95%
Fluorochem EUGermany$0.051 kg95%
AK Scientific SpecializedUnited States$0.051 kg98%
AA BLOCKSUnited States$0.06100 g99%
A2B Chem LLCUnited States$0.06100 g99%
AK Scientific, Inc.United States$0.071 kg99.5%
AstaTech, IncUnited States$0.10500 g95%
ALFA AESARGermany$0.105 kg99%
BLD Pharmatech Co., LimitedUnited States$0.111 kg98%
Ambeed, Inc.United States$0.111 kg98%
Sigma-Aldrich (Rush Stock)Germany$0.121 kg98%
Sigma-AldrichGermany$0.121 kg98%
Apollo Scientific UKUnited Kingdom$0.151 kg98%
Cayman EuropeEstonia$0.17500 g98%
Angene International LimitedUnited States$0.22500 g98%
Combi-Blocks, Inc.United States$0.251 kg97%
Fulfilled by MolportLatvia$0.3010 g98%
MedKoo Biosciences, IncUnited States$1.10500 g98%
MedChemExpress MCESweden$10.5025 g99.98%
Apexbio Technology LLCUnited States$15.405 g98.59%
CliniSciences GmbHSwitzerland$32.251 g99%
InterbioscreenHong Kong$34.0010 g95%
MolnovaChina$45.001 g99%
TargetMol ChemicalsChina → United States$50.001 g99.99%
HTS Biochemie InnovationenGermany$170.005 g95%
Labotest KGGermany$217.805000 mg90%
Otava, Ltd.Ukraine$460.00250 mg95%
ChemFacesChina$1500.0020 mg98%
AngeneChina → Hong Kong$4266.6730 mg98%
ChemDiv, Inc.United States$4400.0090 mg90%
Vitas M Chemical LimitedHong Kong$5133.3330 mg90%
Key Organics Ltd.United Kingdom$6900.0010 mg95%
Princeton BioMolecular Research (SC)United States$8000.0015 mg90%
AsinexNetherlands$8651.50100 mg90%
AnalytiCon Discovery - a Division of BRAIN Biotech AGGermany$143748.0010 mg70%

Chemical Identity

CAS59-67-6
PubChem CID938
DTXSIDDTXSID1020932
FormulaC6H5NO2
Mol. Weight123.11 g/mol
SMILESC1=CC(=CN=C1)C(=O)O

Data Sources

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Brief citations

Nicotinic acid (CAS 59-67-6) https://chemicalindependence.com/chemical/59-67-6/ EPA CompTox (DSSTox): DTXSID1020932. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID1020932 PubChem: 938. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/938 EPA Chemical Data Reporting: 59-67-6. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 59-67-6. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 293629 for CAS 59-67-6. Reporting year: 2024. https://usatrade.census.gov/