Flag of the United StatesAmerican Chemical Independence

Acetazolamide

Drug ingredient

CAS 59-66-5

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 59-66-5
US productionNot reported
Import value, 2024$2.0B
Top sourceIreland 63%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293590 · basket

These shares come from HS customs code 293590, which covers 182 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 63%IrelandSG 14%SingaporeIN 7%IndiaCN 7%ChinaCH 2%Switzerland
43 FDA-registered drug labelers
A-S Medication Solutions
Aarkish Pharmaceuticals NJ Inc.
Accord Healthcare Inc.
Advagen Pharma Ltd
Ajanta Pharma USA Inc.
Alembic Pharmaceuticals Inc.
Alembic Pharmaceuticals Limited
American Health Packaging
ANI Pharmaceuticals, Inc.
Aurobindo Pharma Limited
AvKARE
AvPAK
Bryant Ranch Prepack
Chartwell RX, LLC
CTX Lifesciences Pvt. Ltd.
Emcure Pharmaceuticals Limited
Eywa Pharma Inc
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.
Ingenus Pharmaceuticals, LLC
LETCO MEDICAL, LLC
Lifestar Pharma LLC
Major Pharmaceuticals
Marlex Pharmaceuticals, Inc.
Medisca Inc.
Micro Labs Limited
NAKODA CHEMICALS LIMITED
Northwind Health Company, LLC
NuCare Pharmaceuticals,Inc.
NuCare Pharmaceuticlas, Inc.
PD-Rx Pharmaceuticals, Inc.
Professional Compounding Centers of America
Professional Compounding Centers of America dba PCCA
Proficient Rx LP
Regis Technologies Inc.
Spectrum Laboratory Products, Inc.
Strides Pharma Science Limited
Sun Pharmaceutical Industries, Inc.
TRUPHARMA, LLC
Viona Pharmaceuticals Inc
Westminster Pharmaceuticals, LLC
ZAKLADY FARMACEUTYCZNE POLPHARMA S A
Zydus Lifesciences Limited
Zydus Pharmaceuticals (USA) Inc.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

  • •Acetazolamide
  • •Acetazolamide Extended-Release
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$1.51/gA2B Chem LLC
CountryUnited States
Pack$151.00 / 100 g
Purity97%
Vendors18 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

17 more vendors
VendorCountry$/gPackPurity
AA BLOCKSUnited States$1.61100 g98%
AK Scientific SpecializedUnited States$2.7625 g95%
Sigma-Aldrich (Rush Stock)Germany$3.88250 g99%
Sigma-AldrichGermany$3.88250 g99%
AK Scientific, Inc.United States$3.8825 g98%
ALFA AESARGermany$4.2125 g99%
MedKoo Biosciences, IncUnited States$22.0025 g98%
MedChemExpress MCESweden$23.965 g99.97%
Fulfilled by MolportLatvia$26.00500 mg98%
CliniSciences GmbHSwitzerland$32.251 g99%
Labotest KGGermany$453.001000 mg90%
TargetMol Chemicals EUAustria$580.0050 mg99.94%
MolnovaChina$1580.0050 mg99%
Key Organics Ltd.United Kingdom$6900.0010 mg95%
AsinexNetherlands$9292.8050 mg90%
Princeton BioMolecular Research (SC)United States$10500.0010 mg90%
TimTec, LLCUnited States$13333.3330 mg90%

Chemical Identity

CAS59-66-5
PubChem CID1986
DTXSIDDTXSID7022544
FormulaC4H6N4O3S2
Mol. Weight222.3 g/mol
SMILESCC(=O)NC1=NN=C(S1)S(=O)(=O)N

Data Sources

← Back to Dashboard← Back to Health

Brief citations

Acetazolamide (CAS 59-66-5) https://chemicalindependence.com/chemical/59-66-5/ PubChem: 1986. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/1986 EPA TSCA Inventory: CAS 59-66-5. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293590 for CAS 59-66-5. Reporting year: 2024. https://usatrade.census.gov/