Pyrilamine maleate

Drug ingredient

CAS 59-33-6

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 59-33-6
US productionNot reported
Import value, 2024$1.3B
Top sourceChina 32%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293339 · basket

These shares come from HS customs code 293339, which covers 397 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 32%ChinaIN 15%IndiaDE 10%GermanyBE 9%BelgiumCH 8%Switzerland
62 FDA-registered drug labelers
Acme United Corporation
Allegiant Health
ARMY AND AIR FORCE EXCHANGE SERVICE
Bayer HealthCare LLC
Better Living Brands, LLC
Bioventure Healthcare - FZE
Capital Pharma
Capital Pharmaceutical, LLC
Cardinal Health 110, LLC. DBA Leader
Centurion Labs, LLC
CHAIN DRUG MARKETING ASSOCIATION INC
CVS Pharmacy
Discount Drug Mart
DOLGENCORP, LLC
Elysium Pharmaceutical Ltd
Family Dollar Services Inc
Focus Consumer Healthcare, LLC
Geiss, Destin & Dunn Inc.
GM Pharmaceuticals, INC
H E B
Healthlife of USA
JC World Bell Wholesale Co., Inc.
JHK DBA American Safety & First Aid
KALCHEM INTERNATIONAL INC
Keshava Organics Pvt Ltd
Kroger Company
L.N.K. International, Inc.
LABORATORIO MAGNACHEM INTERNATIONAL SRL
Laboratorios Sanfer, S.A. de C.V.
Lil' Drug Store Products, Inc
Malladi Drugs & Pharmaceuticals Limited
Meijer Distribution Inc
Navajo Manufacturing Company Inc.
O Positiv, Inc.
OPMX LLC
Patheon Softgels Inc.
Pharmadel LLC
Pioneer Life Sciences, LLC
Poly Pharmaceuticals, Inc.
Professional Compounding Centers of America
Professional Compounding Centers of America dba PCCA
R J General Corporation
Rite Aid Corporation
Select Consumer Group
Shield Pharmaceuticals Corp
Softgel Healthcare Pvt Ltd
Spectrum Laboratory Products, Inc.
Srikem laboratories Pvt. Ltd.
Strive Pharmaceuticals Inc.
Supriya Lifescience Limited
TARGET
Target Corporation
Thompson Safety
Time Cap Labs, Inc
Topco Associates, LLC
Unifirst First Aid Corporation
United Natural Foods, Inc. dba UNFI
Walgreen Company
WALGREENS CO.
WALMART INC.
Westminster Pharmaceuticals, LLC
WinCo Foods, LLC

Why It Matters

Sectors
Health
Downstream Uses

Appears in 46 drug and cosmetic product listings (FDA).

  • •Menstrual Pain Relief Complete
  • •menstrual pain relief maximum strength
  • •Capron DMT
  • •Menstrual Relief Maximum Strength
  • •Midol Complete
  • •Texaclear Fast Acting Allergy Relief
  • •TexaClear Kids Allergy
  • •Buscapina
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$3.85/gAA BLOCKS
CountryUnited States
Pack$385.00 / 100 g
Purity98%
Vendors4 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS59-33-6
PubChem CID5284451
DTXSIDDTXSID4021216
FormulaC21H27N3O5
Mol. Weight401.5 g/mol
SMILESCN(C)CCN(CC1=CC=C(C=C1)OC)C2=CC=CC=N2.C(=CC(=O)O)C(=O)O

Data Sources

Brief citations

Pyrilamine maleate (CAS 59-33-6) https://chemicalindependence.com/chemical/59-33-6/ PubChem: 5284451. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5284451 EPA TSCA Inventory: CAS 59-33-6. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293339 for CAS 59-33-6. Reporting year: 2024. https://usatrade.census.gov/