Biotin
Drug ingredientCAS 58-85-5
This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.
US productionNot reported
Import value, 2024$295M
Top sourceChina 56%
This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.
Why supply is unknownProduction is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.
Where It Comes From
Customs basis: HS 293629 · basket
These shares come from HS customs code 293629, which covers 17 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.
Source Countries
Country of origin for US imports, from Census customs data (2024).
CN 56%ChinaCH 12%SwitzerlandIN 12%IndiaIT 11%ItalyJP 2%Japan
- Spain
- Netherlands
- Czech Republic
- Israel
- Guyana
- Norway
- Australia
- Taiwan
- Ivory Coast
- Honduras
- South Korea
- Austria
- Colombia
- Brazil
- Mexico
- Belgium
- South Africa
- Turkey
- Hong Kong
- Chile
- Slovenia
- Ecuador
- Sweden
- Vietnam
41 FDA-registered drug labelers
Acella Pharmaceuticals, LLC
Advanced Pharmaceutical Services, Inc. Dba Affordable Quality Pharmaceuticals
Avion Pharmaceuticals, LLC
Beijing JUNGE Technology Co., Ltd.
Beijing Sea Heart International Science And Technology Co.,Ltd.
BonGeo Pharmaceuticals, Inc.
DSM Nutritional Products, LLC
Exeltis USA, Inc.
Guangdong Aimu Biological Technology Co., Ltd
Guangdong Bisutang Biotechnology Co., Ltd.
Guangzhou Ariel Biotech Co., Ltd.
Guangzhou Binsi Clothing Co.,Ltd.
Guangzhou Borderless Technology Co., Ltd.
Guangzhou Oupeng Cosmetics Co., Ltd
Hahnemann Laboratories, INC.
Hillestad Pharmaceuticals USA
InLight Creation, LLC.
Kolive Cell Co., Ltd.
Lianjiang Shanlilai E-commerce Co., Ltd.
Liddell Laboratories, Inc.
Medisca Inc.
NURAY CHEMICALS PRIVATE LIMITED
Nutritional Specialties, Inc.
Oncora Pharma, LLC
Professional Complementary Health Formulas
Pure Source, LLC
PureTek Corporation
Putian Licheng District Zhijiancheng Trading Co., Ltd.
QINGDAO TIDA BIOTEK CO.,LTD
Sandoz Inc
Shenzhen Boyimei Technology Co., Ltd.
Shenzhen Ctrip Technology Co., Ltd.
Shenzhen Earth Surface Trading Co., Ltd.
Shenzhen Joyuflsh Technology Co.,Ltd.
Spectrum Laboratory Products, Inc.
STHREE CHEMICALS PRIVATE LIMITED
U.S. Pharmaceutical Corporation
Willow Birch Pharma, LLC
Yiwu Pu Feather Trading Co., LTD
Zhejiang Kingland Pharmaceutical Company Limited
Zhejiang Shengda Bio-Pharm Co., Ltd.
Why It Matters
Sectors
Health
Downstream Uses
Appears in 83 drug and cosmetic product listings (FDA).
- •Kweqdsd 5% Minoxidil Hair Growth Sprays Serum
- •Cypkeb 5% Minoxidil Hair Growth Sprays Serum
- •Erwcnmie 5% Minoxidil Hair Growth Sprays Serum
- •5% Minoxidil Hair Growth Topical Solution
- •5% minoxidil with biotin topical solution
- •Dialyvite
- •Integra Plus
- •Floriva
Show all 83
- •Biotitum
- •5% Minoxidil Hair Growth Serum
- •5% Minoxidil Hair Growth Foam
- •Tagoqhia 5% Minoxidil Hair Growth Sprays Serum
- •Aflora
- •Venrock
- •Concept OB
- •Prenate Restore
- •Prenate Pixie
- •Frnoip 5% Minoxidil Hair Growth Sprays Serum
- •Ocvwjkd 5% Minoxidil Hair Growth Sprays Serum
- •Tacruitf 5% minoxidil with biotin topical solution
- •Folartex
- •Folixia
- •Nutralyn
- •Koi Beauty 5% Minoxidil Hair Growth Serum
- •PNV-Omega
- •Folitin-Z
- •Prenate Enhance
- •Erylveka 5% Minoxidil Hair Growth Foam with Biotin
- •Sidinox 5% Minoxidil Hair Growth Foam with Biotin
- •FluMisch Minoxidil Foam
- •Behatmh 5% Minoxidil HAIR Regrowth Serum With Biotin
- •Naliopi 5% minoxidil with biotin topical solution
- •Dialyvite 5000
- •Dialyvite 3000
- •Livita Children
- •Biotin Drops 2081
- •Vita-Rx Diabetic Vitamin
- •Prenate Elite
- •Prenate Mini
- •Meori Toktok
- •5%Minoxidil Hair Growth Sprays Serum
- •Qidila 5% Minoxidil Foam
- •Amrwrir 5% Minoxidil Hair Growth Sprays Serum
- •Bliyeogz 5% Minoxidil Hair Growth Sprays Serum
- •Ezbiort 5% Minoxidil Hair Growth Sprays Serum
- •Tagoqha 5% Minoxidil Hair Growth Sprays Serum
- •5% Minoxidil Hair Growth Foam with Biotin
- •Agikenb 5% minoxidil with biotin topical solution
- •Dialyvite with Zinc
- •Ribotin-E
- •Livita Adults
- •Prenate Essential
- •Folaten
- •Bynisep 5% Minoxidil HAIR Growth Serum
- •PNV-Select
- •Vital Skin Hair Nails
- •B Complex Liquescence
- •5% Minoxidil Topical Aerosol(For Men)
- •5% Minoxidil HAIR Regrowth Serum With Biotin
- •Hair Growth
- •Foliflex
- •Strovite One Caplets
- •Trzsfr 5% Minoxidil Hair Growth Sprays Serum
- •iBeaLee 5% Minoxidil Hair Regrowth Solution
- •Koi Beauty 5% Minoxidil Hair Growth Kit
- •E.O.L.
- •Pediatric Infuvite Multiple Vitamins
- •Finazol
- •Zintrexyl-C
- •Aveya Biotin HAIR Growth
- •5% Minoxidil Hair Regrowth Foam
- •FluMisch 5% Minoxidil
- •Tneghc 5% Minoxidil Hair Growth Sprays Serum
- •Dialyvite Supreme D
- •Concept DHA
- •2% Minoxidil Hair Regrowth Foam
- •5% Minoxidil with Biotin
- •Sidinox 5% Minoxidil Hair Growth Sprays Serum
- •Rdvhdlw 5% Minoxidil Hair Growth Foam with Biotin
- •Oniadba 5% Minoxidil Hair Growth Sprays Serum
- •JBA Collagen-Electrolyte Mocktail
- •Diatrol
- •Prenate Chewable
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Vendor Pricing
$34.00/gMedKoo Biosciences, Inc
CountryUnited States
Pack$850.00 / 25 g
Purity98%
Vendors7 available
Prices reflect listed pack sizes. Small research packs run far above bulk rates.
6 more vendors
| Vendor | Country Supplier country. Where available, shows shipping origin. When the supplier ships from a different country than where they are registered, both are shown. Most suppliers show registration country only. | $/g | Pack | Purity |
|---|---|---|---|---|
| Molnova | China | $65.00 | 1 g | 99% |
| ChemBridge Corporation | Kazakhstan | $1860.00 | 100 mg | 90% |
| Life Chemicals Inc. | Ukraine → Canada | $3466.67 | 75 mg | 90% |
| Asinex | Netherlands | $6461.40 | 100 mg | 90% |
| A2B Chem LLC (2 weeks) | United States | $24600.00 | 5 mg | 90% |
| AA BLOCKS (2 weeks) | United States | $24600.00 | 5 mg | 90% |
Chemical Identity
CAS58-85-5
PubChem CID171548
DTXSIDDTXSID7022679
FormulaC10H16N2O3S
Mol. Weight244.31 g/mol
SMILESC1C2C(C(S1)CCCCC(=O)O)NC(=O)N2
Data Sources
- PubChem · compound 171548Retrieved 2026-04-07
- EPA TSCA InventoryRetrieved 2026-04-24
- FDA National Drug Code directoryRetrieved 2026-04-07
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Biotin (CAS 58-85-5) https://chemicalindependence.com/chemical/58-85-5/ PubChem: 171548. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/171548 EPA TSCA Inventory: CAS 58-85-5. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293629 for CAS 58-85-5. Reporting year: 2024. https://usatrade.census.gov/