Pyridoxine hydrochloride
Drug ingredientCAS 58-56-0
Companies reported imports and no US production of this drug ingredient to EPA for 2019.
US productionZero
Import value, 2024$36M
Import volume37.5K lb
Import dependency100%
Top sourceChina 90%
Production is reported production, not a complete census of factories. Production reporting year: 2019. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.
Pyridoxine hydrochloride · US import value by year
2013: $34M · Peak 2018: $60M · 2024: $36M · 2025: $37M
Where It Comes From
Customs basis: HS 293625 · basket
EPA reports by year
- 2019
- US production Zero · Imports 37.5K lb
These shares come from HS customs code 293625, which covers 4 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.
Source Countries
Country of origin for US imports, from Census customs data (2024).
CN 90%ChinaDE 9%GermanyIN 1%India
- Italy
- Poland
- Ecuador
- United Kingdom
- Israel
EPA-registered importers (1)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
First Continental International (Nj)
49 FDA-registered drug labelers
A-S Medication Solutions
Acella Pharmaceuticals, LLC
Actavis Pharma, Inc.
Analog Pharma
Avion Pharmaceuticals, LLC
BioActive Nutritional, Inc.
Bionpharma Inc.,
Blue Heron Pharmaceuticals, LLC
Bryant Ranch Prepack
CarWin Pharmaceutical Associates, LLC
Deseret Biologicals, Inc.
DNA Labs, Inc.
Dr. Donna Restivo DC
DSM Nutritional Products LLC
Duchesnay USA, Inc.
Endo USA, Inc.
Energetix Corporation
Energique, Inc.
Exeltis USA, Inc.
Fresenius Kabi USA, LLC
Guna spa
HF Acquisition Co LLC, DBA HealthFirst
Hillestad Pharmaceuticals USA
Honour Lab Limited
Integrative Health Alliance
Jiangxi Tianxin Pharmaceutical Co., Ltd.
Lydia Co., Ltd.
Meditrend, Inc. DBA Progena Professional Formulations
METHOD PHARMACEUTICALS, LLC
Mission Pharmacal Company
Mylan Institutional LLC
Mylan Pharmaceuticals Inc.
Nucleic Products, LLC
Nutritional Specialties, Inc.
Oncora Pharma, LLC
Particle Dynamics International, LLC
Patrin Pharma, Inc.
Professional Compounding Centers of America
PureTek Corporation
QINGDAO TIDA BIOTEK CO.,LTD
REMEDYREPACK INC.
Sandoz Inc
Seton Pharmaceuticals
Spectrum Laboratory Products, Inc.
STHREE CHEMICALS PRIVATE LIMITED
U.S. Pharmaceutical Corporation
Willow Birch Pharma, LLC
WINDER LABORATORIES, LLC
WOMENS CHOICE PHARMACEUTICALS LLC
Why It Matters
Sectors
Health
Downstream Uses
Appears in 117 drug and cosmetic product listings (FDA).
- •Oxaltem
- •Dialyvite
- •Quflora Pediatric
- •Spinalmax
- •Glucoreg
- •Nestabs Prenatal Multi-vitamin/Mineral Supplement
- •Integra Plus
- •Diclegis
Show all 117
- •Flotrex
- •Davimet-M
- •Prenatryl
- •Ventrixyl Fe
- •Vitafol One
- •Vitafol Fe Plus
- •Aflora
- •GUNA-Liver
- •Bio Cytotox Phase
- •Bio Co-Enzyme Phase
- •Mitochondria PRO
- •Concept OB
- •D-138
- •M-Natal Plus
- •Vitrexate
- •Venexa
- •Doxylamine Succinate and Pyridoxine Hydrochloride
- •Neuro-Chord
- •Prenate Restore
- •Prenate Pixie
- •Folartex
- •Folixia
- •Nutralyn
- •Se-Tan PLUS
- •N-17
- •PureVit DualFe Plus
- •Vitranol Fe
- •Pretrate
- •Folitin-Z
- •Multi-Vit-Flor
- •Prenate Enhance
- •Dialyvite 5000
- •Dialyvite 3000
- •Prenatal Vitamins Plus Low Iron
- •Pyridoxine HCI
- •D-105
- •Prenatrix
- •Multitam
- •Livita Children
- •Prenate Elite
- •Prenate Mini
- •Dialyvite with Zinc
- •TriStart DHA
- •Multitol-M
- •Menatrol
- •Davimet with Iron
- •Vitrexyl plus Iron
- •Ribotin-E
- •Livita Adults
- •Metal-Chord
- •Hypothalmapath
- •Multivitamin with Fluoride
- •Prenate Essential
- •Lunavira
- •Folaten
- •GUNA-Dizzy
- •GUNA-CELL
- •PNV-Select
- •CitraNatal 90 DHA
- •Vitrexate FE
- •Ventrixyl
- •Vitramyn
- •Davimet
- •Viru-Chord
- •Novominsyrup
- •B Complex Liquescence
- •Vitafol Ultra
- •Omeosport
- •BP Vit 3
- •Sinus Tonic
- •Nestabs ONE
- •N-16
- •Prenatol-M
- •Davimet with Fluoride
- •Foliflex
- •Vitamin B Complex
- •Prenatal Plus Vitamins
- •Hypothaltem
- •Prenate DHA
- •Methylation Assist Liquescence
- •Cellular Oxygenator
- •Strovite One Caplets
- •Lumavex
- •Matronex
- •Se-Natal 19 Chewable
- •Melatonin Forte
- •Pediatric Infuvite Multiple Vitamins
- •Multi-Vitamin Drops with Fluoride and Iron
- •Finazol
- •Vitrexyl
- •Vitranol
- •Zintrexyl-C
- •Dexatran
- •Pyridoxine Hydrochloride
- •Essential Weight LOSS
- •Dialyvite Supreme D
- •Se-Natal 19
- •Concept DHA
- •Progena Immugen
- •PMS
- •Bonjesta
- •Multivitamin
- •Diatrol
- •Prometa
- •Venexa FE
- •NS Support
- •Thyropath
- •Prenate Chewable
- •Cobalefol
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Industrial Uses
- •Flavoring and nutrient in Pharmaceutical and Medicine Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
Vendor Pricing
$0.08/gAaron Chemicals LLC
CountryHong Kong
Pack$41.00 / 500 g
Purity98%
Vendors34 available
Prices reflect listed pack sizes. Small research packs run far above bulk rates.
33 more vendors
| Vendor | Country Supplier country. Where available, shows shipping origin. When the supplier ships from a different country than where they are registered, both are shown. Most suppliers show registration country only. | $/g | Pack | Purity |
|---|---|---|---|---|
| Angene Chemical | China → Hong Kong | $0.09 | 500 g | 98% |
| A2B Chem LLC | United States | $0.11 | 500 g | 98% |
| AA BLOCKS | United States | $0.12 | 500 g | 98% |
| Chemscene | United States | $0.15 | 500 g | — |
| BLD Pharmatech GmbH | Germany | $0.15 | 1 kg | 95% |
| BLD Pharmatech Ltd. | China | $0.15 | 1 kg | 95% |
| Ambeed, Inc. | United States | $0.15 | 1 kg | 95% |
| BLD Pharmatech Co., Limited | United States | $0.15 | 500 g | 95% |
| AK Scientific Specialized | United States | $0.15 | 500 g | 97% |
| Fluorochem EU | Germany | $0.16 | 500 g | 98% |
| MedChemExpress MCE | Sweden | $0.19 | 500 g | — |
| Fulfilled by Molport | Latvia | $0.20 | 25 g | — |
| Combi-Blocks, Inc. | United States | $0.25 | 1 kg | 98% |
| Apollo Scientific US | United Kingdom | $0.29 | 1 kg | 95% |
| AK Scientific, Inc. | United States | $0.30 | 500 g | 99% |
| Fluorochem UK | United Kingdom | $0.46 | 25 g | 98% |
| Angene International Limited | United States | $0.53 | 500 g | 99% |
| ALFA AESAR | Germany | $0.87 | 500 g | 99% |
| AstaTech, Inc | United States | $1.40 | 25 g | 95% |
| MedKoo Biosciences, Inc | United States | $1.45 | 1 kg | 98% |
| Sigma-Aldrich (Rush Stock) | Germany | $3.40 | 100 g | 98% |
| Sigma-Aldrich | Germany | $3.40 | 100 g | 98% |
| Interbioscreen | Hong Kong | $129.00 | 10 g | 95% |
| Molnova | China | $174.00 | 500 mg | 99% |
| TargetMol Chemicals | China → United States | $194.00 | 500 mg | 99.99% |
| Apexbio Technology LLC | United States | $220.00 | 500 mg | 99.81% |
| Labotest KG | Germany | $453.00 | 1000 mg | 90% |
| Specs | Netherlands | $548.13 | 1 g | 90% |
| ChemBridge Corporation | Kazakhstan | $1860.00 | 100 mg | 90% |
| Otava, Ltd. | Ukraine | $2724.00 | 50 mg | 95% |
| Life Chemicals Inc. | Ukraine → Canada | $3100.00 | 100 mg | 90% |
| Angene | China → Hong Kong | $4266.67 | 30 mg | 98% |
| Key Organics Ltd. | United Kingdom | $6900.00 | 10 mg | 99% |
Chemical Identity
CAS58-56-0
PubChem CID6019
DTXSIDDTXSID1040792
FormulaC8H12ClNO3
Mol. Weight205.64 g/mol
SMILESCC1=NC=C(C(=C1O)CO)CO.Cl
Data Sources
- EPA CompTox (DSSTox) · DTXSID1040792Retrieved 2026-04-06
- PubChem · compound 6019Retrieved 2026-04-06
- EPA Chemical Data ReportingReporting year: 2019 · Retrieved 2026-10-04
- FDA National Drug Code directoryRetrieved 2026-04-07
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
Pyridoxine hydrochloride (CAS 58-56-0) https://chemicalindependence.com/chemical/58-56-0/ EPA CompTox (DSSTox): DTXSID1040792. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID1040792 PubChem: 6019. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/6019 EPA Chemical Data Reporting: 58-56-0. Reporting year: 2019. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 58-56-0. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293625 for CAS 58-56-0. Reporting year: 2024. https://usatrade.census.gov/