Ethacrynic acid

Drug ingredient

CAS 58-54-8

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$370M

Top sourceIndia 45%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291899 · basket

These shares come from HS customs code 291899, which covers 139 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IN 45%IndiaCN 35%ChinaGB 7%United KingdomCO 3%ColombiaCH 3%Switzerland

Austria
Hungary
South Korea
Taiwan
Czech Republic
Mexico
Spain
Ukraine
Estonia
Australia
Israel
Singapore
Slovakia
Russia

16 FDA-registered drug labelers

Amneal Pharmaceuticals NY LLC

APICORE PHARMACEUTICALS PRIVATE LIMITED

Bausch Health US, LLC

Bryant Ranch Prepack

Edenbridge Pharmaceuticals LLC.

Egis Pharmaceuticals PLC

Enaltec Labs Private Limited

Lupin Pharmaceuticals, Inc.

Oceanside Pharmaceuticals

Olon S.p.A.

ScieGen Pharmaceuticals Inc

Sionc Pharmaceutical Private Limited

ST. MARY'S MEDICAL PARK PHARMACY

TRUPHARMA LLC

Upsher-Smith Laboratories, LLC

Zydus Lifesciences Limited

Why It Matters

Sectors

Health

Downstream Uses

Appears in 2 drug and cosmetic product listings (FDA).

•Ethacrynic Acid
•Edecrin

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$61.10/gA2B Chem LLC

CountryUnited States

Pack$611.00 / 10 g

Purity99.85%

Vendors18 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

17 more vendors

Vendor	Country	$/g	Pack	Purity
MedKoo Biosciences, Inc	United States	$62.50	20 g	98%
AA BLOCKS	United States	$67.80	10 g	95%
AstaTech, Inc	United States	$91.20	5 g	95%
Combi-Blocks, Inc.	United States	$96.00	5 g	95%
Cayman Europe	Estonia	$97.22	10 g	98%
Ramidus AB	Sweden	$140.00	1 g	—
TargetMol Chemicals	China → United States	$296.00	500 mg	99.99%
Labotest KG	Germany	$453.00	1000 mg	90%
TargetMol Chemicals EU	Austria	$640.00	100 mg	99.99%
Molnova	China	$700.00	100 mg	99%
Apexbio Technology LLC	United States	$725.00	200 mg	98.35%
MedChemExpress MCE	Sweden	$1185.80	100 mg	99.98%
Synthonix	United States	$1200.00	100 mg	95%
Sigma-Aldrich (Rush Stock)	Germany	$2610.40	200 mg	—
Sigma-Aldrich	Germany	$2610.40	200 mg	—
AK Scientific, Inc.	United States	$2720.00	25 mg	95%
TimTec, LLC	United States	$13333.33	30 mg	90%

Chemical Identity

CAS58-54-8

PubChem CID3278

DTXSIDDTXSID3025257

FormulaC13H12Cl2O4

Mol. Weight303.13 g/mol

SMILESCCC(=C)C(=O)C1=C(C(=C(C=C1)OCC(=O)O)Cl)Cl

Data Sources

PubChem · compound 3278Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Ethacrynic acid (CAS 58-54-8) https://chemicalindependence.com/chemical/58-54-8/ PubChem: 3278. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/3278 FDA National Drug Code directory: CAS 58-54-8. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 291899 for CAS 58-54-8. Reporting year: 2024. https://usatrade.census.gov/