promethazine hydrochloride
Drug ingredientActive ShortageThis drug ingredient is in active FDA shortage. At least one manufacturer cannot meet demand.
Where It Comes From
58 FDA-registered drug labelers
A-S Medication Solutions
Actavis Pharma, Inc.
Advanced Rx Pharmacy of Tennessee, LLC
American Health Packaging
Amneal Pharmaceuticals LLC
Amneal Pharmaceuticals of New York LLC
ANI Pharmaceuticals, Inc.
ASCLEMED USA INC.
ATLANTIC BIOLOGICALS CORP
BluePoint Laboratories
Bryant Ranch Prepack
Camber Pharmaceuticals, Inc.
Cardinal Health 107, LLC
Catalent Micron Technologies, Inc.
Chartwell Governmental & Specialty RX, LLC.
Chartwell RX, LLC
Cosette Pharmaceuticals, Inc.
Coupler LLC
Cranbury Pharmaceuticals, LLC
DIRECT RX
Egis Pharmaceuticals PLC
Emcure Pharmaceuticals Limited
EUROAPI FRANCE
Fagron Inc
Genus Lifesciences Inc.
Henry Schein, Inc.
HF Acquisition Co. LLC, DBA HealthFirst
Hikma Pharmaceuticals USA Inc.
KALCHEM INTERNATIONAL INC
Kesin Pharma Corporation
KVK-Tech, Inc.
Major Pharmaceuticals
Medical Purchasing Solutions, LLC
Medisca Inc.
NCS HealthCare of KY, LLC dba Vangard Labs
Northwind Health Company, LLC
Nostrum Laboratories, Inc.
NuCare Pharmaceuticals,Inc.
Padagis Israel Pharmaceuticals Ltd
PAI Holdings, LLC dba PAI Pharma
PD-Rx Pharmaceuticals, Inc.
PharmPak, Inc.
Preferred Pharmaceuticals Inc.
PROFESSIONAL COMPOUNDING CENTERS OF AMERICA
Professional Compounding Centers of America dba PCCA
Proficient Rx LP
ProPharma Distribution
QUAGEN PHARMACEUTICALS LLC
REMEDYREPACK INC.
Sanofi Winthrop Industrie
Sigma-Aldrich Ireland Ltd.
Solupharm Pharmazeutische Erzeugnisse GmbH
Sportpharm, Inc. dba Sportpharm
St. Mary's Medical Park Pharmacy
XGen Pharmaceuticals DJB, Inc.
Xttrium Laboratories, Inc
Zydus Lifesciences Limited
Zydus Pharmaceuticals USA Inc.
Why It Matters
Sectors
Health
Downstream Uses
Appears in 12 drug and cosmetic product listings (FDA).
- •Promethazine Hydrochloride
- •Promethegan
- •Promethazine Hydrochloride and Phenylephrine Hydrochloride
- •Promethazine and Phenylephrine HCl, and Codeine Phosphate
- •Promethazine Hydrochloride and Dextromethorphan Hydrobromide
- •Promethazine Hydrochloride and Codeine Phosphate
- •Promethazine
- •Promethazine DM
Show all 12
- •Promethazine Hydrochloride and Dextromethorphan Hydrobromide Oral
- •Promethazine Hydrochloride and Dextromethorphan Hydrobromide Oral Solution
- •Phenergan
- •Promethazine HCI
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
Active Shortage
Shortage History
Each row is a separate manufacturer's FDA shortage filing — not a timeline for the drug as a whole. Multiple "current" entries are normal: each manufacturer/NDC files independently. Status reflects the manufacturer's report; reason describes their supply situation (Available, Unavailable, or to be discontinued).
current
Promethazine Hydrochloride Injection
11/21/2023Available
current
Promethazine Hydrochloride Injection
11/21/2023Unavailable
Vendor Pricing
$1.10/gAaron Chemicals LLC
CountryHong Kong
Pack$548.00 / 500 g
Purity98%
Vendors22 available
Prices reflect listed pack sizes. Small research packs run far above bulk rates.
21 more vendors
| Vendor | Country Supplier country. Where available, shows shipping origin. When the supplier ships from a different country than where they are registered, both are shown. Most suppliers show registration country only. | $/g | Pack | Purity |
|---|---|---|---|---|
| Angene Chemical | China → Hong Kong | $1.17 | 500 g | 98% |
| A2B Chem LLC | United States | $1.20 | 100 g | 98% |
| Combi-Blocks, Inc. | United States | $1.20 | 100 g | 98% |
| AA BLOCKS | United States | $1.40 | 100 g | 98% |
| Sigma-Aldrich (Rush Stock) | Germany | $2.68 | 100 g | — |
| Sigma-Aldrich | Germany | $2.68 | 100 g | — |
| Cayman Europe | Estonia | $2.95 | 50 g | 95% |
| AK Scientific, Inc. | United States | $4.64 | 25 g | 98% |
| AstaTech, Inc | United States | $4.92 | 25 g | 95% |
| Angene International Limited | United States | $5.82 | 100 g | 98% |
| MedChemExpress MCE | Sweden | $12.58 | 5 g | 99.85% |
| MedKoo Biosciences, Inc | United States | $15.00 | 50 g | 98% |
| TargetMol Chemicals | China → United States | $29.00 | 1 g | 99.85% |
| Molnova | China | $43.00 | 1 g | 99% |
| Apexbio Technology LLC | United States | $55.00 | 1 g | 98.63% |
| CliniSciences GmbH | Switzerland | $64.50 | 500 mg | 99% |
| Labotest KG | Germany | $453.00 | 1000 mg | 90% |
| AK Scientific Specialized | United States | $680.00 | 100 mg | 99% |
| Angene | China → Hong Kong | $4266.67 | 30 mg | 98% |
| Key Organics Ltd. | United Kingdom | $6900.00 | 10 mg | 97% |
| TimTec, LLC (back-ordered) | United States | $32000.00 | 15 mg | 94% |
Chemical Identity
CAS58-33-3
PubChem CID6014
DTXSIDDTXSID3021192
FormulaC17H21ClN2S
Mol. Weight320.9 g/mol
SMILESCC(CN1C2=CC=CC=C2SC3=CC=CC=C31)N(C)C.Cl
Data Sources
60142026-04-07
https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/name/promethazine hydrochloride/cids/JSON
Archive: data/sources/pubchem_name/promethazine hydrochloride.json
CAS 58-33-32026-04-24
https://www.epa.gov/tsca-inventory
Archive: data/sources/tsca/tsca_inventory.csv
CAS 58-33-32026-06-13
https://api.fda.gov/drug/shortages.json
Archive: data/sources/fda/shortages/shortages.json