Desipramine hydrochloride

Drug ingredient

CAS 58-28-6

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 58-28-6
1 HCl
US productionNot reported
Import value, 2024$1.4B
Top sourceIreland 33%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293399 · basket

These shares come from HS customs code 293399, which covers 518 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 33%IrelandCN 26%ChinaIN 11%IndiaDE 9%GermanyIT 4%Italy
11 FDA-registered drug labelers
Actavis Pharma, Inc.
Alembic Pharmaceuticals Inc.
Alembic Pharmaceuticals Limited
Amneal Pharmaceuticals NY LLC
Chartwell RX, LLC
Direct_Rx
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.
Ingenus Pharmaceuticals, LLC
Lundbeck Pharmaceuticals Italy S.p.A.
PCAS FINLAND OY
Validus Pharmaceuticals LLC

Why It Matters

Sectors
Health
Downstream Uses

Appears in 3 drug and cosmetic product listings (FDA).

  • •Desipramine Hydrochloride
  • •Norpramin
  • •Desipramine HCL
FDA Shortage Status
No Shortage
Shortage History
  • to be discontinued

    Desipramine Hydrochloride Tablet

    Shortage listed since August 12, 2025

See all current drug shortages

Vendor Pricing

$28.00/gCombi-Blocks, Inc.
CountryUnited States
Pack$280.00 / 10 g
Purity98%
Vendors25 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS58-28-6
PubChem CID65327
DTXSIDDTXSID9046942
FormulaC18H23ClN2
Mol. Weight302.8 g/mol
SMILESCNCCCN1C2=CC=CC=C2CCC3=CC=CC=C31.Cl

Data Sources

Brief citations

Desipramine hydrochloride (CAS 58-28-6) https://chemicalindependence.com/chemical/58-28-6/ PubChem: 65327. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/65327 FDA National Drug Code directory: CAS 58-28-6. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 58-28-6. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293399 for CAS 58-28-6. Reporting year: 2024. https://usatrade.census.gov/