Flag of the United StatesAmerican Chemical Independence

Menadione

Drug ingredient

CAS 58-27-5

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 58-27-5
US productionNot reported
Import value, 2024$35M
Top sourceChina 49%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291469 · basket

These shares come from HS customs code 291469, which covers 31 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 49%ChinaIN 17%IndiaJP 11%JapanNL 9%NetherlandsIT 8%Italy
5 FDA-registered drug labelers
Deseret Biologicals, Inc.
Dr. Donna Restivo DC
Energique, Inc.
Nutritional Specialties, Inc.
Professional Complementary Health Formulas

Why It Matters

Sectors
Health
Downstream Uses

Appears in 8 drug and cosmetic product listings (FDA).

  • •Menadione 1528
  • •Dairy Allergen Mix
  • •Bone Liquescence
  • •Multi-Phenolic
  • •Allermilk
  • •Menadione Phenolic
  • •D1 Organ Support
  • •Detox I
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$0.26/gAaron Chemicals LLC
CountryHong Kong
Pack$132.00 / 500 g
Purity98%
Vendors33 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

32 more vendors
VendorCountry$/gPackPurity
A2B Chem LLCUnited States$0.29500 g98%
Angene ChemicalChina → Hong Kong$0.31500 g98%
AA BLOCKSUnited States$0.38500 g98%
Combi-Blocks, Inc.United States$0.381 kg98%
BLD Pharmatech Co., LimitedUnited States$0.441 kg98%
BLD Pharmatech Ltd.China$0.441 kg98%
Ambeed, Inc.United States$0.441 kg98%
Fluorochem UKUnited Kingdom$0.45250 g98%
BLD Pharmatech GmbHGermany$0.52500 g98%
AK Scientific, Inc.United States$0.52500 g98%
AK Scientific SpecializedUnited States$0.54100 g95%
AstaTech, IncUnited States$0.7850 g95%
Apollo Scientific UKUnited Kingdom$0.781 kg98%
Angene International LimitedUnited States$0.87500 g98%
Cayman EuropeEstonia$1.39250 g95%
Sigma-Aldrich (Rush Stock)Germany$2.89100 g—
Sigma-AldrichGermany$2.89100 g—
MedKoo Biosciences, IncUnited States$4.90500 g98%
CliniSciences GmbHSwitzerland$32.251 g98%
InterbioscreenHong Kong$34.0010 g95%
MedChemExpress MCESweden$34.9710 g99.82%
Apexbio Technology LLCUnited States$62.001 g98.5%
MolnovaChina$88.001 g99%
TargetMol ChemicalsChina → United States$98.001 g99.41%
Labotest KGGermany$453.001000 mg90%
Maybridge, Ltd.United Kingdom$2414.30100 mg90%
Otava, Ltd. (2 weeks)Ukraine$2724.0050 mg90%
AngeneChina → Hong Kong$4266.6730 mg98%
Key Organics Ltd.United Kingdom$6900.0010 mg95%
TimTec, LLCUnited States$9333.3330 mg90%
Vitas M Chemical LimitedHong Kong$14000.005 mg90%
Princeton BioMolecular Research (SC)United States$18000.005 mg90%

Chemical Identity

CAS58-27-5
PubChem CID4055
DTXSIDDTXSID4021715
FormulaC11H8O2
Mol. Weight172.18 g/mol
SMILESCC1=CC(=O)C2=CC=CC=C2C1=O

Data Sources

← Back to Dashboard← Back to Health

Brief citations

Menadione (CAS 58-27-5) https://chemicalindependence.com/chemical/58-27-5/ PubChem: 4055. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/4055 EPA TSCA Inventory: CAS 58-27-5. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 291469 for CAS 58-27-5. Reporting year: 2024. https://usatrade.census.gov/