methyltestosterone

Drug ingredient

CAS 58-18-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$154M

Top sourceItaly 60%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293729 · basket

These shares come from HS customs code 293729, which covers 57 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IT 60%ItalyES 14%SpainCN 11%ChinaDE 6%GermanyAT 2%Austria

Netherlands
Australia
Malaysia
Portugal
United Kingdom
Japan
Malta
Canada
Israel
Singapore
New Zealand
Poland
Ukraine
Belgium
Sweden

17 FDA-registered drug labelers

Amneal Pharmaceuticals of New York LLC

ANI Pharmaceuticals, Inc.

ASG Biochem Pvt. LTD

Aspen Oss B.V.

Bryant Ranch Prepack

Creekwood Pharmaceuticals LLC

ECI Pharmaceuticals LLC

Farmabios S.p.A.

Leading Pharmaceuticals, LLC

LETCO MEDICAL, LLC

Method Pharmaceuticals

Method Pharmaceuticals, LLC

NURAY CHEMICALS PRIVATE LIMITED

Professional Compounding Centers of America

Professional Compounding Centers of America dba PCCA

STATUS PROJECTS PRIVATE LIMITED

Symbiotec Pharmalab Limited

Why It Matters

Sectors

Health

Downstream Uses

Appears in 7 drug and cosmetic product listings (FDA).

•Estratest FS
•Esterified Estrogens and Methyltestosterone
•MethylTESTOSTERone
•Methitest
•Estratest HS
•Esterified Estrogens AND Methyltestosterone HALF Strength
•Esterified Estrogens AND Methyltestosterone FULL Strength

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS58-18-4

PubChem CID6010

DTXSIDDTXSID1033664

FormulaC20H30O2

Mol. Weight302.5 g/mol

SMILESCC12CCC(=O)C=C1CCC3C2CCC4(C3CCC4(C)O)C

Data Sources

PubChem · compound 6010Retrieved 2026-04-07
EPA TSCA InventoryRetrieved 2026-04-24
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

methyltestosterone (CAS 58-18-4) https://chemicalindependence.com/chemical/58-18-4/ PubChem: 6010. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/6010 EPA TSCA Inventory: CAS 58-18-4. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293729 for CAS 58-18-4. Reporting year: 2024. https://usatrade.census.gov/