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Clozapine

Drug ingredient

CAS 5786-21-0

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 5786-21-0
US productionNot reported
Import value, 2024$7.6B
Top sourceIreland 61%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293359 · basket

These shares come from HS customs code 293359, which covers 295 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 61%IrelandCH 30%SwitzerlandGB 2%United KingdomCN 2%ChinaIN 1%India
21 FDA-registered drug labelers
Accord Healthcare Inc.
American Health Packaging
Aurobindo Pharma Limited
AX Pharmaceutical Corp
Bryant Ranch Prepack
Cambrex Profarmaco Milano Srl
Cardinal Health 107, LLC
Cohance Lifesciences Limited
HLS Therapeutics (USA), Inc.
Major Pharmaceuticals
Matrix Pharmacorp Private Limited
Medichem S.A.
Mylan Institutional Inc.
Mylan Pharmaceuticals Inc.
Patheon Manufacturing Services LLC
R.L.Fine Chem Private Limited
Safecor Health LLC
Shouguang Fukang Phamaceutical Co., Ltd.
SMS Pharmaceuticals Limited
Teva Pharmaceuticals USA, Inc.
TruPharma LLC

Why It Matters

Sectors
Health
Downstream Uses

Appears in 3 drug and cosmetic product listings (FDA).

  • •Clozapine
  • •Versacloz
  • •Clozaril
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$0.65/gAaron Chemicals LLC
CountryHong Kong
Pack$327.00 / 500 g
Purity98%
Vendors20 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

19 more vendors
VendorCountry$/gPackPurity
Angene ChemicalChina → Hong Kong$0.66500 g98%
A2B Chem LLCUnited States$0.87500 g99.93%
AA BLOCKSUnited States$1.14500 g98%
Biopharma PEG Scientific Inc.United States$2.50100 g98%
Fulfilled by MolportLatvia$10.00500 mg99%
AK Scientific SpecializedUnited States$47.405 g95%
AK Scientific, Inc.United States$66.405 g98%
Angene International LimitedUnited States$109.005 g98%
InterbioscreenHong Kong$129.0010 g95%
AstaTech, IncUnited States$277.001 g97%
MedChemExpress MCESweden$537.241 g99.84%
Cayman EuropeEstonia$618.80500 mg98%
TargetMol ChemicalsChina → United States$920.00100 mg99.95%
CliniSciences GmbHSwitzerland$1225.50100 mg99%
Sigma-Aldrich (Rush Stock)Germany$2407.551 g—
Sigma-AldrichGermany$2407.551 g—
Axon MedchemNetherlands$2640.0050 mg99%
AngeneChina → Hong Kong$4266.6730 mg99%
Key Organics Ltd.United Kingdom$6900.0010 mg97%

Chemical Identity

CAS5786-21-0
PubChem CID135398737
DTXSIDDTXSID5022855
FormulaC18H19ClN4
Mol. Weight326.8 g/mol
SMILESCN1CCN(CC1)C2=NC3=C(C=CC(=C3)Cl)NC4=CC=CC=C42

Data Sources

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Brief citations

Clozapine (CAS 5786-21-0) https://chemicalindependence.com/chemical/5786-21-0/ PubChem: 135398737. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/135398737 FDA National Drug Code directory: CAS 5786-21-0. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293359 for CAS 5786-21-0. Reporting year: 2024. https://usatrade.census.gov/