Docusate sodium

Drug ingredient

CAS 577-11-7

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

Molecular structure of 577-11-7
1 Na⁺
US productionCBI
Import value, 2024$139M
Top sourceChina 67%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 291719 · basket

EPA reports by year
2023
US production Confidential · Imports Confidential
2019
US production Confidential · Imports Confidential

These shares come from HS customs code 291719, which covers 176 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 67%ChinaCA 13%CanadaAT 4%AustriaIN 4%IndiaJP 4%Japan
EPA-registered manufacturers (9)
Syensqo Sa · BE Belgium
Ascent Chemicals
Dow Chemical
Dystar
Innospec
Domestic parents -- activity not disclosed (2)
Cargill, Incorporated
Elementis
EPA-registered importers (10)
Basf Se · DE Germany
Pcc Exol Sa · PL Poland
Arkema
Basf
Daxx
128 FDA-registered drug labelers
A-S Medication Solutions
Advanced Rx LLC
Advanced Rx of Tennessee, LLC
Advanced Rx Pharmacy of Tennessee, LLC
AENOVA ROMANIA S.R.L.
Aldama Pharmaceuticals, Inc
Alexso, Inc
Allegiant Health
Amazon.com Services LLC
American Health Packaging
Amerisource Bergen
AmerisourceBergen (Good Neighbor Pharmacy) 46122
AmerisourceBergen Drug Corp
APL HEALTHCARE LIMITED
APNAR PHARMA LP
Army & Air Force Exchange Service
Asclemed USA, Inc.
ATLANTIC BIOLOGICALS CORP.
Atlantis Consumer Healthcare Inc.
AvPAK
Basic Drugs, Inc.
Bayer HealthCare LLC.
Belleview Bio Science
Best Choice (Valu Merchandisers Company)
BETTER LIVING BRANDS LLC.
Bi-Mart
Bioventure Healthcare - FZE
BJWC (Berkley & Jensen / BJ's)
Brainstorm Industries LLC
Bryant Ranch Prepack
C.B. Fleet Company, Inc.
Cardinal Health
Cardinal Health 107, LLC
CARDINAL HEALTH 110, LLC. DBA LEADER 70000
CARDINAL HEALTH, 110 DBA LEADER
Care One (Retail Business Services, LLC.)
Catalent Ontario Limited
Chain Drug Consortium, LLC
Chain Drug Marketing Association
Chattem, Inc.
Costco Wholesale
CVS HEALTH
CVS Pharmacy
CVS PHARMACY, INC
Discount Drug Mart, Inc
Dolgencorp, Inc. (DOLLAR GENERAL & REXALL)
EQUATE (Wal-Mart Stores, Inc.) (see also WAL-MART INC)
Family Dollar (FAMILY WELLNESS)
Farmacias De Similares TX LLC
Geri-Care Pharmaceutical Corp
GERI-CARE PHARMACEUTICALS, CORP
GOOD SENSE
Good Sense (Geiss, Destin & Dunn, Inc.)
Granulation Technology, Inc.
H E B
HealthLife of USA LLC
Heartland Pharma Co.
HHH Pharmaceuticals
Humanwell PuraCap Pharmaceutical (Wuhan) Co., Ltd.
Humanwell PuraCap Pharmaceutical (Wuhan), Ltd.
Humanwell PuraCap Pharmaceuticals (Wuhan) Co., Ltd
Hunan Jiudian Pharmaceutical Co.,Ltd.
Kesin Pharma Corporation
KROGER
KROGER COMPANY
L. Perrigo Company
LLORENS PHARMACEUTICALS INTERNATIONAL DIVISION
Magno-Humphries, Inc.
MAJOR PHARMACEUTICALS
Marc Glassman, Inc.
Marlex Pharmaceuticals Inc
MEDGEL PRIVATE LIMITED
Meijer Distribution Inc.
MEIJER, INC.
Mission Pharmacal Company
Morepen Laboratories Limited
National Vitamin Company
NCS HealthCare of KY, LLC dba Vangard Labs
NuCare Pharmaceuticals, Inc.
NUVICARE LLC
OPMX LLC
P & L Development, LLC
Padagis Israel Pharmaceuticals Ltd
PAI Holdings, LLC dba PAI Pharma
Patheon Softgels Inc.
PD-Rx Pharmaceuticals, Inc.
Pharbest Pharmaceuticals, Inc.
Physicians Science & Nature Inc.
Pioneer Life Sciences, LLC
Preferred Pharmaceuticals Inc.
Prodose, Inc.
Proficient Rx LP
Publix Supermarkets, Inc.
PuraCap Pharmaceutical LLC
QUALITY CHOICE (Chain Drug Marketing Association)
Quest Products LLC
Reese Pharmaceutical Co
Reliable 1 Laboratories LLC
RMT HEALTH LLC
RUGBY LABORATORIES
Safecor Health, LLC
Safeway, Inc.
Sam's West Inc
Sato Pharmaceutical Co., Ltd.
Seton Pharmaceuticals
Shield Pharmaceuticals Corp
SOFTGEL HEALTHCARE PRIVATE LIMITED
Spectrum Laboratory Products, Inc.
STRATEGIC SOURCING SERVICES LLC
SYNFINE DRUGS PRIVATE LIMITED
TARGET CORPORATION
TCB USA Corporation
Terrain Pharmaceuticals
The Kroger Co.
TIME CAP LABORATORIES, INC
TOP CARE (Topco Associates LLC)
TOPCO ASSOCIATES LLC
Ulai Health LLC
United Natural Foods, Inc. dba UNFI
Village Pharma
VIVUNT PHARMA LLC
Walgreen Co.
WALGREEN COMPANY
Walgreens
WALGREENS CO.
WALMART INC. (see also Equate)
Wanbury Limted
WinCo Foods, LLC

Why It Matters

Sectors
Plastics & RubberPaints & CoatingsPaper & PrintingCore ChemicalsHealthEnergyConsumer ProductsMetals & MiningTextilesAgricultureConstruction
Downstream Uses

Appears in 92 drug and cosmetic product listings (FDA).

  • •Senna-S
  • •Gencare-Senna-S Softgel
  • •Stool Softener Laxative
  • •DOK
  • •Docusate Sodium - Stool Softener Laxative
  • •Docusate Sodium
  • •Docu Liquid
  • •Stool Softener
FDA Shortage Status
No FDA shortage records

Industrial Uses

Used in 19 sectors as 14 functional roles.

  • •Soil amendments (fertilizers) in Pesticide, Fertilizer, and Other Agricultural Chemical ManufacturingNot Known or Reasonably Ascertainable
  • •Filler in Paper Manufacturing (100%)Use—non-incorporative activities
  • •Surfactant (surface active agent) in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Surfactant (surface active agent) in Paint and Coating Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Surfactant (surface active agent) in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (10%)Processing—incorporation into formulation, mixture, or reaction product
  • •Surfactant (surface active agent) in Textiles, apparel, and leather manufacturing (90%)Processing—incorporation into formulation, mixture, or reaction product
  • •Surfactant (surface active agent) in Plastics Product Manufacturing (10%)Processing—incorporation into formulation, mixture, or reaction product
  • •Surfactant (surface active agent) in Non-metallic Mineral Product Manufacturing (includes clay, glass, cement, concrete, lime, gypsum, and other non-metallic mineral product manufacturing) (9%)Processing—incorporation into formulation, mixture, or reaction product
  • •Surfactant (surface active agent) in Mining (except Oil and Gas) and support activities (15%)Processing—incorporation into formulation, mixture, or reaction product
  • •Surfactant (surface active agent) in Adhesive Manufacturing (6%)Processing—incorporation into formulation, mixture, or reaction product
  • •Surfactant (surface active agent) in Petroleum Lubricating Oil and Grease Manufacturing (5%)Processing—incorporation into formulation, mixture, or reaction product
  • •Surfactant (surface active agent) in Pharmaceutical and Medicine Manufacturing (2%)Processing—incorporation into formulation, mixture, or reaction product
  • •Intermediate in Textiles, apparel, and leather manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Viscosity modifiers in Other (1%)Processing—incorporation into formulation, mixture, or reaction product
  • •Surfactant (surface active agent) in All Other Chemical Product and Preparation Manufacturing (20%)Processing—incorporation into formulation, mixture, or reaction product
  • •Flocculating agent in All Other Basic Organic Chemical Manufacturing (5%)Processing—incorporation into formulation, mixture, or reaction product
  • •Surface modifier in Paint and Coating ManufacturingProcessing as a reactant
  • •Emulsifier in Paint and Coating Manufacturing (50%)Processing—incorporation into formulation, mixture, or reaction product
  • •Processing aids, specific to petroleum production in Oil and Gas Drilling, Extraction, and Support activities (50%)Processing—incorporation into formulation, mixture, or reaction product
  • •Adhesion/cohesion promoter in Adhesive Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
  • •Cleaning agent in Agriculture, Forestry, Fishing and Hunting (100%)Processing as a reactant
  • •Adhesion/cohesion promoter in Mining (except Oil and Gas) and support activities (100%)Use—non-incorporative activities
  • •Preservative in Asphalt Paving, Roofing, and Coating Materials ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
  • •Wetting agent (non-aqueous) in Adhesive ManufacturingProcessing—incorporation into article
  • •Preservative in Adhesive ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
  • •Lubricating agent in Fabricated Metal Product ManufacturingUse—non-incorporative activities
  • •Preservative in Paint and Coating ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
  • •Preservative in Not Known or Reasonably AscertainableNot Known or Reasonably Ascertainable

Vendor Pricing

$0.06/gAaron Chemicals LLC
CountryHong Kong
Pack$28.00 / 500 g
Purity96%
Vendors17 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS577-11-7
PubChem CID23673837
DTXSIDDTXSID8022959
FormulaC20H37NaO7S
Mol. Weight444.6 g/mol
SMILESCCCCC(CC)COC(=O)CC(C(=O)OCC(CC)CCCC)S(=O)(=O)[O-].[Na+]

Data Sources

Brief citations

Docusate sodium (CAS 577-11-7) https://chemicalindependence.com/chemical/577-11-7/ EPA CompTox (DSSTox): DTXSID8022959. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID8022959 PubChem: 23673837. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/23673837 EPA Chemical Data Reporting: 577-11-7. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: CAS 577-11-7. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 291719 for CAS 577-11-7. Reporting year: 2024. https://usatrade.census.gov/