Sulfamethazine

Drug ingredient

CAS 57-68-1

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$2.0B

Top sourceIreland 63%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293590 · basket

These shares come from HS customs code 293590, which covers 182 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IE 63%IrelandSG 14%SingaporeIN 7%IndiaCN 7%ChinaCH 2%Switzerland

Portugal
Spain
Italy
Austria
Israel
Hungary
Canada
South Korea
Netherlands
Finland
Poland
Indonesia
Ukraine
Mexico
South Africa
Croatia
Greece
Taiwan
Hong Kong

3 FDA-registered drug labelers

Hunan Wugan Pharmaceutical Co., Ltd.

Hunan Xiangyikang Pharmaceutical Co., Ltd.

Second Pharma Co., Ltd.

Why It Matters

Sectors

Health

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Vendor Pricing

$0.05/gAaron Chemicals LLC

CountryHong Kong

Pack$25.00 / 500 g

Purity99%

Vendors28 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

27 more vendors

Vendor	Country	$/g	Pack	Purity
Angene Chemical	China → Hong Kong	$0.06	500 g	99%
A2B Chem LLC	United States	$0.08	500 g	95%
AA BLOCKS	United States	$0.10	500 g	99%
AK Scientific Specialized	United States	$0.25	1 kg	98%
Combi-Blocks, Inc.	United States	$0.25	1 kg	95%
Cayman Europe	Estonia	$0.76	250 g	98%
ALFA AESAR	Germany	$0.94	100 g	99%
Sigma-Aldrich (Rush Stock)	Germany	$1.16	100 g	101%
Sigma-Aldrich	Germany	$1.16	100 g	101%
AK Scientific, Inc.	United States	$1.42	250 g	99%
Angene International Limited	United States	$2.33	250 g	99%
Apexbio Technology LLC	United States	$5.00	10 g	99.6%
Fluorochem UK	United Kingdom	$7.15	1 g	98%
MedChemExpress MCE	Sweden	$16.21	10 g	99.47%
TargetMol Chemicals	China → United States	$90.00	500 mg	99.88%
AstaTech (2 weeks)	United States	$204.00	500 mg	95%
Labotest KG	Germany	$217.80	5000 mg	90%
Vitas M Chemical Limited	Hong Kong	$360.00	1 g	90%
ChemBridge Corporation	Kazakhstan	$1860.00	100 mg	90%
Otava, Ltd.	Ukraine	$2724.00	50 mg	90%
Princeton BioMolecular Research (SC)	United States	$2900.00	100 mg	90%
ChemDiv, Inc.	United States	$4070.00	100 mg	90%
Angene	China → Hong Kong	$4266.67	30 mg	99%
Asinex	Netherlands	$6461.40	100 mg	90%
Key Organics Ltd.	United Kingdom	$6900.00	10 mg	97%
Life Chemicals Inc.	Ukraine → Canada	$7266.67	15 mg	90%
TimTec, LLC	United States	$16000.00	30 mg	90%

Chemical Identity

CAS57-68-1

PubChem CID5327

DTXSIDDTXSID6021290

FormulaC12H14N4O2S

Mol. Weight278.33 g/mol

SMILESCC1=CC(=NC(=N1)NS(=O)(=O)C2=CC=C(C=C2)N)C

Data Sources

PubChem · compound 5327Retrieved 2026-04-07
EPA TSCA InventoryRetrieved 2026-04-24
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Sulfamethazine (CAS 57-68-1) https://chemicalindependence.com/chemical/57-68-1/ PubChem: 5327. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/5327 EPA TSCA Inventory: CAS 57-68-1. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293590 for CAS 57-68-1. Reporting year: 2024. https://usatrade.census.gov/