Probenecid

Drug ingredient

CAS 57-66-9

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 57-66-9
US productionNot reported
Import value, 2024$2.0B
Top sourceIreland 63%

This chemical is listed as active in US commerce, but no company reported it to EPA’s survey for 2019 or 2023. Sites may have made or imported less than the threshold amount, or none.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293590 · basket

These shares come from HS customs code 293590, which covers 182 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 63%IrelandSG 14%SingaporeIN 7%IndiaCN 7%ChinaCH 2%Switzerland
11 FDA-registered drug labelers
Actavis Pharma, Inc.
Assia Chemical Industries Ltd - Teva Tech Site
Bryant Ranch Prepack
Cohance Lifesciences Limited
Ingenus Pharmaceuticals, LLC
ITERUM THERAPEUTICS US LIMITED
Lannett Company, Inc.
Marlex Pharmaceuticals Inc
Medisca Inc.
Rising Pharma Holdings, Inc.
SCL Lifesciences Limited

Why It Matters

Sectors
Health
Downstream Uses

Appears in 3 drug and cosmetic product listings (FDA).

  • •Probenecid
  • •Probenecid and Colchicine
  • •Orlynvah
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$0.90/gCombi-Blocks, Inc.
CountryUnited States
Pack$450.00 / 500 g
Purity97%
Vendors23 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS57-66-9
PubChem CID4911
DTXSIDDTXSID9021188
FormulaC13H19NO4S
Mol. Weight285.36 g/mol
SMILESCCCN(CCC)S(=O)(=O)C1=CC=C(C=C1)C(=O)O

Data Sources

Brief citations

Probenecid (CAS 57-66-9) https://chemicalindependence.com/chemical/57-66-9/ PubChem: 4911. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/4911 EPA TSCA Inventory: CAS 57-66-9. Retrieved 2026-04-24. https://www.epa.gov/tsca-inventory FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293590 for CAS 57-66-9. Reporting year: 2024. https://usatrade.census.gov/