1,2-Propylene glycol
Drug ingredientCAS 57-55-6
This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.
US productionCBI
Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.
Import value, 2024$29M
Top sourceSouth Korea 52%
At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.
Why supply is unknownProduction is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023.
Where It Comes From
Customs basis: HS 290532 · narrow
EPA reports by year
- 2023
- US production Confidential · Imports Confidential
- 2019
- US production Confidential · Imports Confidential
HS 290532 covers only 1,2-Propylene glycol, so these shares are 1,2-Propylene glycol's own.
Source Countries
Country of origin for US imports, from Census customs data (2024).
KR 52%South KoreaDE 19%GermanyCN 8%ChinaSG 7%SingaporeBE 3%Belgium
- Italy
- Japan
- Taiwan
- United Kingdom
- Switzerland
- Israel
- Poland
- United Arab Emirates
EPA-registered manufacturers (14)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Indorama Netherlands Bv · NL Netherlands
Syensqo Sa · BE Belgium
Archer Daniels Midland
Brenntag
Dow Chemical
Show all 14
Icl Specialty Products North America
Indorama Ventures Usa Holdings
Inland Coatings
Lyondell Chemical
Macdermid
Minerals Technologies
Proviron
Solvay
Solvchem
Domestic parents -- activity not disclosed (20)
EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.
A.G. Layne
Aalborz Chemical
Allchem Industries Holding
Ch Biotech
Chemical Distribution Network
Show all 20
Chemours
Coast Southwest
Colonial Group
Fci
Flint Group Packaging Inks North America Holdings
Henkel Us Operations
Ineos Enterprises Us Hold
Makhteshim Agan Of North America, Inc. Dba Adama
Polyventive
Reckitt Benckiser
Stepan
Superior Industrial Solutions
Tauber Petrochemical
Third Coast Packaging
Vitusa Products
EPA-registered importers (63)
Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.
Archroma Management Gmbh · CH Switzerland
Basf Se · DE Germany
Cci Holding · JP Japan
Clariant International · CH Switzerland
Heubach Holding S R L · LU Luxembourg
Show all 63
Indorama Netherlands Bv · NL Netherlands
Lamberti S P A · IT Italy
Mercedes-Benz Group Ag · DE Germany
Reckitt Benckiser Group · GB United Kingdom
Syensqo Sa · BE Belgium
Symrise Ag · DE Germany
Unid Global · KR South Korea
Ab Enzymes
Aceto Us
Ambyth Chemical
Archroma U.S
Avient
Basf
Brenntag Lubricants
Canon U.S.A
Catalynt Solutions
Cci Manufacturing Il
Clariant
Colgate-Palmolive
Croda
Daxx
Delta Carbona
Enco Manufacturing
Givaudan Fragrances
Greenchem Industries
Haifa North America
Hallmark Cards
Harris Paints
Helm America
Heubach Holding Usa
Hilti
Hollyfrontier Lsp Us Holding
Independent Chemical
Innospec
International Flavors And Fragrances
Lamberti Usa
Lanco Manufacturing
Mercedes-Benz Vans
Milliken &
Oci International
Quadra Chemicals
Recochem
Ricoh Usa
S.C. Johnson & Son
Sensient Colors
Silver Fern Chemical
Solenis
Soyventis North America
Stratasys
Symrise
Takasago
Target
The Sherwin Williams
Univar Solutions
Venator Chemicals
Wego Chemical Group
Wilbur-Ellis Holdings Ii
Wintersun International
Why It Matters
Sectors
FoodPlastics & RubberPaints & CoatingsElectronicsTransportationPaper & PrintingCore ChemicalsHealthEnergyConsumer ProductsMetals & MiningWaterTextilesAgricultureConstruction
Downstream Uses
Appears in 97 drug and cosmetic product listings (FDA).
- •Systane Lubricant
- •Systane Complete PF
- •Anubis Barcelona Regul Oil
- •Anubismed
- •Quality Choice Lubricant Eye Drops Restorative Performance
- •Quality Choice Lubricant Eye Drops Long Lasting
- •Feelshion Glycolic Acid Exfoliating Face Pads
- •Rite Aid Hydration Lubricant Eye Drops
Show all 97
- •CVS Long Lasting Lubricant Eye Drops 15mL
- •Walgreens Lubricant Eye Drops Dry Eye 15mL and twin pack
- •Walgreens Lubricant
- •Leader Restorative Formula Lubricant Eye Drops
- •Equate Complete Relief Lubricant Eye Drops
- •Anubis Barcelona New Even
- •Eyewash Station Additive Concentrate
- •Rohto Optic Glow
- •Target Lubricant Eye Drops High Performance
- •Signature Care Lubricant Eye Drops Long Lasting
- •Sunmark Lubricant Eye Drops
- •Family Care Ultra Lubricant
- •Harris Teeter Ultra Lubricant Eye Drops
- •Systane Hydration PF Preservative FREE
- •CorneaCare Recover Lubricant Eye Drops
- •Quality Choice
- •Ocusan Dry Eyes
- •Kroger High Performance Lubricant Eye Drops
- •Petrochemical Detox
- •Leader Lubricant Eye Drops 30ct
- •Leader Ultra Lubricating Eye Drops
- •Systane
- •Vista Meibo Tears Propylene Glycol 0.6% w/v Advanced Dry Eye Relief Lubricating Drops 10 ml
- •Target Lubricant Eye Drops Restorative Performance
- •Pneumotox
- •Household Antigens
- •Equate Lubricant Eye Drops
- •Health Mart Lubricating Tears
- •Eyewash Additive Concentrate
- •Artificial Tears Lubricant Eye Drops
- •Foster and Thrive Long Lasting Lubricant Eye Drops
- •Systane Balance
- •Systane Ultra Preservative Free
- •artificial tears
- •Rite Aid Lubricant Eye Drops Restorative Performance
- •Enviroclenz
- •Equate Lubricant Eye Drops Restorative Performance
- •Instant Hand Sanitizeing Wipe
- •Anubis Barcelona Protective Line
- •Quality Choice Lubricant Eye Drops High Performance
- •Rohto Dry-Aid
- •Topcare Health Lubricant Eye Drops
- •HEB Lubricant Eye Drops Dry Eye Therapy
- •Splash Pure PF
- •Foster and Thrive Lubricating Tears Lubricant Eye Drops
- •Systane Ultra
- •Revitalize Energizing Eye Drops
- •Anubis Barcelona
- •Quality Choice Lubricant
- •Signature Care Eye Drops High Performance
- •CVS Health Fast Acting Lubricant Eye Drops
- •CVS Lubricant Eye Drops 15mL
- •Dry eye relief
- •Leader Preservative-Free Ultra Lubricating Eye Drops
- •Systane Pro PF
- •Baby Wipes
- •Archies Dry Eye Relief
- •Lubricant Eye Drops
- •Sunmark Lubricating Tears
- •CVS Hydration Eye Drops
- •Walgreens Lubricant Eye Drops High Performance 15mL and twin pack
- •GenTeal Tears Gel Drops
- •Avenova Lubricant Eye Drops High Performance
- •Bestmade Natural Products BM235
- •Eghmtw hair oil
- •Rohto Preservative Free Dry Aid
- •Advanced Eye Relief Dry Eye Rejuvenation
- •Meijer Lubricant Eye Drops
- •GNP Eye Drops Long Lasting
- •GoodSense Ultra Lubricant Eye Drops
- •Exchange Select High Performance Lubricant Eye Drops
- •OneDrop
- •Walgreens Lubricant Eye Drops Restorative Performance
- •Walgreens Ultra Lubricant
- •CVS Lubricant Eye Drops Original
- •Anubis Barcelona Spa Line
- •Droptics Performance Eye Drops
- •Optiq Balance
- •Soothe
- •Meijer Ultra Lubricant Eye Drops High Performance
- •Envirotox
- •Equate Lubricant Eye Drops High Performance
- •Artifical Tears
- •Lubricant Eye Drops Solution
- •Medics Choice Fresh and Soothe Lubricant Eye Drops
- •DG Lubricant Eye Drops
- •Publix High Performance Eye Drops
- •Leader Lubricant Eye Drops Fast-Acting Hydration
- •Systane Complete
FDA Shortage Status
Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."
No FDA shortage records
Industrial Uses
Used in 29 sectors as 35 functional roles.
- •Humectant in All Other Chemical Product and Preparation Manufacturing (100%)Processing—repackaging
- •Fragrance in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (1%)Processing—incorporation into formulation, mixture, or reaction product
- •Fragrance in All Other Chemical Product and Preparation Manufacturing (99%)Processing—incorporation into formulation, mixture, or reaction product
- •Viscosity modifiers in Plastics Material and Resin ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Dye in Wood Product Manufacturing (1%)Processing—incorporation into formulation, mixture, or reaction product
- •Soil amendments (fertilizers) in Agriculture, Forestry, Fishing and Hunting (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Heat transferring agent in All Other Basic Organic Chemical ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Monomers in Plastics Material and Resin ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Anti-freeze agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Solvent in Printing Ink ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Solvent in Printing and Related Support ActivitiesProcessing—incorporation into formulation, mixture, or reaction product
- •Surface modifier in Paint and Coating Manufacturing (99%)Processing—incorporation into formulation, mixture, or reaction product
- •Viscosity modifiers in Paint and Coating Manufacturing (1%)Processing—incorporation into formulation, mixture, or reaction product
- •Diluent in Pharmaceutical and Medicine Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Corrosion inhibitor in Paint and Coating Manufacturing (35%)Processing—incorporation into formulation, mixture, or reaction product
- •Tanning agents not otherwise specified in Paint and Coating Manufacturing (8%)Processing—incorporation into formulation, mixture, or reaction product
- •Anti-stain agent in Paint and Coating Manufacturing (10%)Processing—incorporation into formulation, mixture, or reaction product
- •Solvent in Agriculture, Forestry, Fishing and Hunting (1%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in All other Petroleum and Coal Products Manufacturing (27%)Processing as a reactant
- •Solvent in All Other Chemical Product and Preparation Manufacturing (4%)Processing—incorporation into formulation, mixture, or reaction product
- •Solvent in Paint and Coating Manufacturing (11%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in Wholesale and Retail Trade (45%)Processing—repackaging
- •Solvent in Food, beverage, and tobacco product manufacturing (4%)Processing—incorporation into formulation, mixture, or reaction product
- •Film former in Synthetic Dye and Pigment ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Lubricating agent in Synthetic Dye and Pigment ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Solvent in Pesticide, Fertilizer, and Other Agricultural Chemical ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Stabilizing agent in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (10%)Processing—incorporation into formulation, mixture, or reaction product
- •Stabilizing agent in Wood Product Manufacturing (90%)Processing as a reactant
- •Dye in Printing Ink Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Solvent in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Lubricating agent in Wholesale and Retail Trade (1%)Processing—incorporation into formulation, mixture, or reaction product
- •Anti-freeze agent in Wholesale and Retail Trade (80%)Processing—incorporation into formulation, mixture, or reaction product
- •Heat transferring agent in Wholesale and Retail Trade (18%)Processing—incorporation into formulation, mixture, or reaction product
- •Monomers in All Other Basic Organic Chemical Manufacturing (100%)Processing as a reactant
- •Surface modifier in Asphalt Paving, Roofing, and Coating Materials Manufacturing (100%)Processing as a reactant
- •Intermediate in All Other Basic Organic Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Solvent in Other (10%)Processing—incorporation into formulation, mixture, or reaction product
- •Diluent in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (40%)Processing—incorporation into formulation, mixture, or reaction product
- •Solvent in All Other Basic Organic Chemical Manufacturing (30%)Processing—incorporation into formulation, mixture, or reaction product
- •Flavoring and nutrient in Food, beverage, and tobacco product manufacturing (35%)Processing—incorporation into formulation, mixture, or reaction product
- •Surfactant (surface active agent) in Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •CBI in CBICBI
- •Viscosity modifiers in Oil and Gas Drilling, Extraction, and Support activities (5%)Processing—incorporation into formulation, mixture, or reaction product
- •Solvent in Furniture and Related Product ManufacturingUse—non-incorporative activities
- •Solvent in Miscellaneous ManufacturingUse—non-incorporative activities
- •Solvent in Transportation Equipment ManufacturingUse—non-incorporative activities
- •Solvent in Wood Product ManufacturingUse—non-incorporative activities
- •Solvent in Electrical Equipment, Appliance, and Component ManufacturingUse—non-incorporative activities
- •Solvent in Construction (3%)Use—non-incorporative activities
- •Emulsifier in All Other Basic Organic Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Preservative in Food, beverage, and tobacco product manufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Surfactant (surface active agent) in Oil and Gas Drilling, Extraction, and Support activities (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Heat transferring agent in All Other Chemical Product and Preparation Manufacturing (10%)Processing—incorporation into formulation, mixture, or reaction product
- •Intermediate in Plastics Material and Resin Manufacturing (100%)Processing—repackaging
- •Defoamer in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Corrosion inhibitor in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Plating agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Chelating agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Etching agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Flux agent in All Other Chemical Product and Preparation ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Solvent in Paper Manufacturing (55%)Use—non-incorporative activities
- •Solvent in Synthetic Dye and Pigment Manufacturing (55%)Processing—incorporation into formulation, mixture, or reaction product
- •Solvent in Textiles, apparel, and leather manufacturing (45%)Use—non-incorporative activities
- •Stabilizing agent in Plastics Material and Resin Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Hardener in Paint and Coating Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Solubility enhancer in Wholesale and Retail Trade (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Humectant in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Stabilizing agent in Food, beverage, and tobacco product manufacturing (50%)Processing—incorporation into formulation, mixture, or reaction product
- •Emulsifier in Food, beverage, and tobacco product manufacturing (50%)Processing—incorporation into formulation, mixture, or reaction product
- •Plasticizer in Paint and Coating Manufacturing (91%)Processing—incorporation into formulation, mixture, or reaction product
- •Plasticizer in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (9%)Processing—incorporation into formulation, mixture, or reaction product
- •Diluent in Primary Metal Manufacturing (100%)Processing—incorporation into article
- •Dispersing agent in Pesticide, Fertilizer, and Other Agricultural Chemical ManufacturingProcessing—incorporation into formulation, mixture, or reaction product
- •Dispersing agent in Oil and Gas Drilling, Extraction, and Support activitiesProcessing—incorporation into formulation, mixture, or reaction product
- •Fragrance in Other (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Diluent in Soap, Cleaning Compound, and Toilet Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Anti-freeze agent in Transportation Equipment ManufacturingProcessing—incorporation into article
- •Anti-adhesive/cohesive in All Other Basic Organic Chemical Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Heat transferring agent in Paint and Coating Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Waterproofing agent in All Other Chemical Product and Preparation Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Monomers in Electrical Equipment, Appliance, and Component ManufacturingProcessing as a reactant
- •Dye in Paper ManufacturingProcessing—incorporation into article
- •Pigment in Plastics Material and Resin ManufacturingProcessing—incorporation into article
- •Monomers in ConstructionProcessing as a reactant
- •Surface modifier in Fabricated Metal Product ManufacturingProcessing—incorporation into article
- •Pigment in Synthetic Dye and Pigment Manufacturing (100%)Processing—incorporation into formulation, mixture, or reaction product
- •Dispersing agent in Paint and Coating ManufacturingNot Known or Reasonably Ascertainable
- •Lubricating agent in Machinery Manufacturing (3%)Processing—incorporation into article
Vendor Pricing
$0.01/gAaron Chemicals LLC
CountryHong Kong
Pack$6.00 / 1 kg
Purity99%
Vendors23 available
Prices reflect listed pack sizes. Small research packs run far above bulk rates.
22 more vendors
| Vendor | Country Supplier country. Where available, shows shipping origin. When the supplier ships from a different country than where they are registered, both are shown. Most suppliers show registration country only. | $/g | Pack | Purity |
|---|---|---|---|---|
| Angene Chemical | China → Hong Kong | $0.01 | 1 kg | 99% |
| Sigma-Aldrich (Rush Stock) | Germany | $0.01 | 30 kg | 99.5% |
| Sigma-Aldrich | Germany | $0.01 | 30 kg | 99.5% |
| Manchester Organics | United Kingdom | $0.02 | 900 g | 98% |
| A2B Chem LLC | United States | $0.02 | 1 kg | 99% |
| AA BLOCKS | United States | $0.02 | 1 kg | 99% |
| BLD Pharmatech Co., Limited | United States | $0.02 | 1 kg | 99% |
| Ambeed, Inc. | United States | $0.02 | 1 kg | 99% |
| BLD Pharmatech GmbH | Germany | $0.03 | 1 kg | — |
| BLD Pharmatech Ltd. | China | $0.03 | 1 kg | — |
| Chemscene | United States | $0.05 | 1 kg | — |
| Fluorochem EU | Germany | $0.06 | 1 kg | 98% |
| Fluorochem UK | United Kingdom | $0.07 | 1 kg | 98% |
| AK Scientific Specialized | United States | $0.08 | 500 g | 98% |
| AK Scientific, Inc. | United States | $0.11 | 500 g | 99% |
| Combi-Blocks, Inc. | United States | $0.25 | 1 kg | 99% |
| Angene International Limited | United States | $0.41 | 500 g | 99% |
| Interbioscreen | Hong Kong | $10.00 | 10 g | 95% |
| Labotest KG | Germany | $217.80 | 5000 mg | 90% |
| A2B Chem LLC (1 week) | United States | $930.00 | 500 mg | 98% |
| AA BLOCKS (1 week) | United States | $1026.00 | 500 mg | 98% |
| Angene | China → Hong Kong | $4266.67 | 30 mg | 95% |
Chemical Identity
CAS57-55-6
PubChem CID1030
DTXSIDDTXSID0021206
FormulaC3H8O2
Mol. Weight76.09 g/mol
SMILESCC(CO)O
Data Sources
- EPA CompTox (DSSTox) · DTXSID0021206Retrieved 2026-04-06
- PubChem · compound 1030Retrieved 2026-04-06
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
- US Census international tradeReporting year: 2024 · Retrieved 2026-10-04
Brief citations
1,2-Propylene glycol (CAS 57-55-6) https://chemicalindependence.com/chemical/57-55-6/ EPA CompTox (DSSTox): DTXSID0021206. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID0021206 PubChem: 1030. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/1030 EPA Chemical Data Reporting: 57-55-6. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 57-55-6. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 290532 for CAS 57-55-6. Reporting year: 2024. https://usatrade.census.gov/